Prolotherapy or stimulating injection therapy is an alternative treatment method to reduce chronic musculoskeletal pain that activates the body's natural healing process by injecting stimulating substances (such as dextrose solution) into the damaged tissues. What is prolotherapy and how does it work? This treatment involves injecting stimulating solutions into specific areas of the body that are damaged or weak, such as ligaments, tendons, or joints. These injections cause controlled inflammation that stimulates the body to begin the process of tissue repair and regeneration. What conditions is it used for? Prolotherapy is commonly used to treat chronic pain and musculoskeletal problems, including: - Arthritis (knee prolotherapy, especially knee arthritis) - Chronic back and neck pains - tendinopathies (such as tennis elbow) - Joint pains caused by sports injuries - Fibromyalgia What are the benefits of prolotherapy? - Non-surgical: This treatment is a non-invasive method that does not require surgery. - Stimulation of the body's natural repair: by stimulating the natural repair processes, it helps to restore damaged tissues. - Reducing chronic pain: Studies have shown that it can be effective in reducing chronic pain. What are the possible complications and risks? While this treatment is generally considered safe, it may have some side effects: - Temporary pain and stiffness: temporary pain or stiffness may occur in the injection area. - Bruising and swelling: bruising or swelling may be seen at the injection site. - Infection: although rare; But there is a possibility of infection at the injection site. Allergic reactions: Some people may have allergic reactions to injectables. How is prolotherapy performed? During a session, the doctor injects a stimulating solution into the affected area. This process may be repeated several times by the pain specialist depending on the severity and type of injury. Who should not? - People with bleeding disorders: people who have blood clotting problems. - People with active infection: if there is an infection in the desired area. - People with allergies to injectable substances: people who are allergic to the substances used in prolotherapy. How is the treatment process? - Initial evaluation: the doctor determines the appropriateness of this treatment method by examining the medical history and physical examination. - Treatment sessions: Depending on the severity and type of problem, several treatment sessions may be needed at specific time intervals. - Post-injection care: Resting, using ice and avoiding heavy activities will help recovery. Can it replace surgery? In some patients, yes. If the injury is not severe enough to require surgery, this treatment method can be an effective option to improve function and reduce pain, especially in people who are not candidates for surgery.