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Awareness of the most dangerous nerve pill available in the market guarantees your health and prevents the sometimes dangerous side effects of taking such drugs. Although doctors emphasize that self-administration of any type of medicine is very dangerous and risky, some people still take medicines without medical advice without sufficient knowledge. Due to the importance of these cases, in this article, we will try to examine these drugs with your doctor in more detail along with how to take them. Stay with us.
Which nerve pills are dangerous?
Some drugs cause neurological or systemic damage if used incorrectly. Drugs such as isoniazid, metronidazole, colchicine, excessive intake of vitamin B6, and exposure to heavy metals such as arsenic have been associated with peripheral neuropathy, especially if taken long-term. In the field of neuropsychiatric drugs, the main risk is usually related to central nervous system depression, dependence, drug poisoning, and dangerous interactions, which are more common in some drug groups.
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Benzodiazepines
- benzodiazepine-like sleeping pills
- tricyclic antidepressants
- Lithium and the risk of poisoning
- Some high-risk antipsychotic drugs (such as clozapine)

1. Benzodiazepines
Benzodiazepines are among the the most powerful nerve pills and are sedatives that reduce anxiety, induce sleep, and relax muscles by reducing the activity of the central nervous system. These drugs are usually prescribed for the short-term treatment of anxiety, insomnia, or seizures. The main risk of benzodiazepines is dependence, drug tolerance and withdrawal symptoms. Long-term use of this drug causes memory impairment, severe drowsiness, increased risk of falling (especially in the elderly) and, in high doses, constriction and difficulty breathing.
2. benzodiazepine-like sleeping pills
Z-drugs such as zolpidem, zopiclone, and azopiclone are chemically different from benzodiazepines, but have similar effects on GABA receptors. These drugs are prescribed for the treatment of insomnia and, compared to benzodiazepines, in some patients with a lower risk of dependence, abnormal sleep behaviors, cognitive impairment and increased risk of accidents; Especially if they are taken with alcohol or other sedatives.
English text:
quoted from ncbi.nlm.nih
Z-drugs are associated with dependence, cognitive impairment, and complex sleep behaviors.
Persian translation:
Z-drugs are associated with dependence, cognitive impairment, and complex sleep behaviors.
3. Tricyclic antidepressants
Tricyclic antidepressants such as amitriptyline and Imipramine is one of the old but effective drugs that affect brain neurotransmitters. In addition to depression, these drugs are sometimes used for chronic pain and migraine.
The risk of this drug group is mostly related to heart complications, blood pressure drop, arrhythmia and poisoning in overdose. For this reason, they are prescribed with great caution in elderly patients or those with heart disease.
4. Lithium and the risk of poisoning
Lithium is one of the main drugs for the treatment of bipolar disorder, which has a small distance between therapeutic and toxic doses. Elevated lithium levels can cause tremors, nausea, confusion, and imbalance. In severe cases, lithium poisoning can lead to seizures, coma, brain damage, and death. Dehydration, kidney disorder and simultaneous use of some drugs increase the risk of poisoning caused by the use of this drug.
5. Some high-risk antipsychotic drugs (such as clozapine)There are many high-risk antipsychotic drugs that you should be aware of. Antipsychotic drugs are used to treat psychosis and are divided into two groups, typical and atypical.
Antipsychotic medications can help reduce or relieve symptoms associated with psychosis. They may also help with anxiety and agitation and problems with mood, thinking, and socializing. Some antipsychotics work better if you also receive psychotherapy and social support.
| Drug group of nerves | Examples (example) | The most important risk or complication |
|---|---|---|
| Benzodiazepines | Diazepam, Lorazepam, Alprazolam | Drug dependence and tolerance, Withdrawal symptoms, memory impairment, severe drowsiness, increased risk of falls and, in high doses, respiratory depression |
| benzodiazepine-like sleeping pills (Z-drugs) | zolpidem, zopiclone, ezopiclone | dependence, abnormal sleep behaviors, cognitive impairment, increased risk of accidents (especially with alcohol) |
| tricyclic antidepressants | amitriptyline, imipramine | cardiac complications, arrhythmia, hypotension and dangerous poisoning in overdose |
| mood stabilizers (lithium) | lithium carbonate | poisoning due to the low therapeutic and toxic dose interval; Trembling, confusion, seizures, coma and brain damage |
| some high-risk antipsychotic drugs | clozapine | severe systemic and hematological side effects, need for regular monitoring and the risk of drug interactions |
| non-specific drugs with a neurological effect when used incorrectly | isoniazid, metronidazole, colchicine, vitamins B6 (high dose) | Peripheral neuropathy, especially in long-term use |
| Alcohol and CNS depressants (with neuroleptics) | — | Intensification of suppression of the central nervous system, decreased level of consciousness and risk of respiratory arrest |
Danger of food and drug interactions with nerve pills
Some foods change the effectiveness of neuroleptics. For example, by inhibiting liver enzymes, grapefruit increases the blood level of some anti-depressant and anti-anxiety drugs and increases the risk of side effects. Alcohol also has one of the most dangerous interactions; Because together with nerve pills, it causes severe suppression of the central nervous system, lowering the level of consciousness and even respiratory arrest.

Which people are most at risk of nerve pills?
People who take several nerve drugs at the same time or have a history of alcohol and drug use are at high risk. These compounds make the effects of drugs unpredictable. Athletes or people with nerve or muscle injuries are also more sensitive to some drugs; Especially if the drug causes a decrease in alertness or motor coordination.
In addition, children, the elderly and people with underlying diseases are more exposed to the side effects of nerve agents than others. The nervous system of these people is more sensitive and the possibility of poisoning or severe complications is higher in them. Also, people with liver, kidney, or heart diseases may experience drug accumulation and dangerous side effects more quickly due to impaired drug excretion.
English text:
Medicines used to treat nerve pain usually act on natural chemicals (neurotransmitters) in the body's nervous system. Most work by 'calming down' nerve activity to reduce your nerves' hypersensitivity (strong reaction) to a pain cause. Farsi translation: Medicines used to treat nerve pain usually act on natural chemicals (neurotransmitters) in the body's nervous system. Most of them work by calming nerve activity to reduce nerve hypersensitivity (overreaction) to the cause of pain.Conclusion
The most dangerous nerve pill is not necessarily a specific drug; Rather, it is a drug that is used without proper diagnosis, without medical supervision, or incorrectly. Many of these drugs are effective and life-saving if used correctly. آگاهی از عوارض احتمالی مصرف دارو، تداخلات احتمالی مصرف آن و اطلاع از گروههای پرخطر، نقش مهمی در پیشگیری از آسیبهای جدی و گاه جبرانناپذیر دارد.
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