What is Gilbert's syndrome?

**What is Gilbert's syndrome podcast.. Listen:**

**About 7% of people suffer from Gilbert's syndrome.... This disease is actually an increase in the concentration of bilirubin in the blood.... Bilirubin is a waste product from the breakdown of red blood cells.... Most of this disease appears as Jaundice is with a person from birth... although the symptoms of the disease may not appear until the age of 20 to 40 years.. Properly excreting bilirubin and increasing the concentration of bilirubin in the blood causes yellowing of the skin.**

**In the context of the inheritance of this disease, if one of the parents is suffering from this disease, the probability of passing its single gene to each of the children and its complications is 50%.** **In this disease, which is a benign syndrome, liver enzymes are normal... Jaundice that occurs in patients can be low or high, but these patients do not have any symptoms caused by liver diseases such as nausea and vomiting, anorexia or pain in the upper abdomen.** **In the tests that the doctor requests for the patient, the only positive point is the high "indirect bilirubin", while the liver enzymes are high and there are no signs of destruction of red blood cells.** #### **What is the cause of jaundice in patients with Gilbert's syndrome?** **The liver does not function well in excreting bilirubin in the bile, which causes the level of bilirubin in the blood to be higher than normal... If the level of bilirubin in the blood exceeds a certain limit, jaundice may appear... Of course, these symptoms do not have special or dangerous consequences for the person... If there is a problem in the liver related to this disease, it is usually mild.** #### **Symptoms of Gilbert's syndrome** **Usually, other family members and most of the time the mother of the family notices yellow eyes in children, which is sometimes low and sometimes high.. The patient does not have symptoms of liver disease such as nausea, vomiting, anorexia, etc., and in the tests that the doctor requests for the patient, the only positive point is the high "Bailizi" and liver loss.. It is also a sign of destruction of red blood cells... It doesn't have.** #### ** Ways to diagnose Gilbert syndrome *** ** This syndrome can be diagnosed by examining the liver and spleen and performing some blood tests.... Ultrasound of the liver and spleen is also another diagnostic method.... Rifampin test is also used as a diagnostic test, in a way that increases the amount of bilirubin in the patients' serum.** **The effect of rifampin in increasing the serum bilirubin level of patients with Gilbert's disease compared to healthy individuals is investigated... Although rifampin can be a suitable criterion for diagnosing Gilbert's syndrome (with high sensitivity), the increase of bilirubin is considered higher than normal after the administration of Rifamp*. #### **Syndrome treatment Gilbert** **Gilbert's disease is not a serious disease and its treatment is possible by identifying the cause of the disease in the person and eliminating it... Accordingly, if the cause of the disease is severe physical activity, reducing the amount of physical activity is necessary to treat the disease and improve the person.** **Many sufferers of this syndrome complain about its external symptoms, such as yellowing of the eyes and skin... For this reason, it can be reduced by following some tips: Avoiding hunger, thirst and excessive fatigue (such as heavy and long-term sports) - Avoiding nervous tension, anxiety and depression - Avoiding smoking, alcohol and drugs - Having a full night.**' **Using "folic acid" also has an effective role in the treatment of Gilbert's disease.** **Folic acid has also been effective in the recovery of some sufferers.... Folic acid deficiency is considered one of the causes of this syndrome.... This disease is a benign hereditary disorder and has nothing to do with reducing life expectancy... Affected people can lead a normal life (marriage, birth of children) like other people and there is no reason to worry**.. ** Avoiding hunger, consuming more liquids and sugary substances and reducing nervous pressure are effective in preventing this disease.** **Colds also cause an increase in blood "bilirubin" in some of these people, yellowing of the whites of the eyes, and Gilbert's disease.** #### **Gilbert syndrome disease diet** **Diet rich in protein and low in fat, consumption of liquids and various vitamins are naturally effective in the recovery of affected people. Among the types of food effective in the treatment of Gilbert's syndrome, we can mention cabbage, cauliflower, broccoli, carrots, beets, plums, blackberries, blueberries, dandelion flower infusion, horsetail, fish oil, and walnuts.** #### **Drugs** **Phenobarbital: reduces bilirubin, phenobarbital activates UDPGT enzyme, which increases the excretion of bilirubin through urine.** **Clofibrate** **glycine, glutamic acid, cysteine, methionine** **The amino acid taurine also plays an important role in improving the function of the liver in the elimination of toxins.** ** Folic acid has also been effective in the recovery of some patients... Folic acid deficiency is one of the factors that increases the production of bilirubin in the ineffective hematopoietic process.** **Note: It is not recommended to take these drugs without consulting a doctor.** > Dr. Mehdi Afzal Aghaei, a specialist in digestive and liver diseases in Mashhad, has a specialized board > > Performing endoscopy and colonoscopy in the office with anesthesia and without pain with the lowest cost and the best quality for the well-being of dear patients > > To schedule an appointment, you can call (051) 38704066 every day... > > Office address: Mashhad, Kausar Blvd., between Kausar 2 and 4 - Farabi Building - 2nd floor **Gastroenterologist in Mashhad** ==================================== **\*Gastroenterologist in Mashhad\***
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