Advanced operation of artificial cornea and stem cell transplantation For patients suffering from severe corneal damage from burns or chronic inflammation of the ocular surface from Stevens-Johnson syndrome and pemphigoid, treatment of corneal opacities with a natural corneal graft will not help. Also, in cases where the patient has undergone natural cornea transplant surgery several times and the transplant was rejected, re-doing these cornea transplant cases will not be successful. Transplantation or transplantation of stem cells is necessary.. In what cases are stem cells done?. Corneal stem cells are located in a place called limbus, which is the border between the cornea and the sclera. These cells play a role in the regeneration of the corneal surface (epithelium) through gradual proliferation. Corneal cells can be donated from the patient's healthy eye, a close relative of the patient, or from an artificial eye. In patients who have undergone natural cornea transplant surgery several times and suffered transplant rejection, and people who have severe eyelid injuries and dry eyes, if they have the conditions to perform the operation, they are candidates for artificial cornea transplant. In the following, we briefly explain the two methods of this link: ### Boston cornea or Boston KPRO Type1 Boston corneas, which have received FDA approval since 1992, have been transplanted into the eyes of more than 19,000 people... In many patients who are candidates for corneal transplantation, the natural human cornea is the best choice. Corneal grafting using the bone tissue of the tooth is known as osteo-odonto, which is connected to the transplanted tissue through a tissue keratoprosthesis. A part of the oral mucosa and alveolar bone is made into a set that is a suitable platform for placing an artificial cornea. The important point in choosing an artificial cornea transplant method is that the nerve and retina of the eye must be healthy for the surgery to have a good result. Otherwise, corneal transplantation cannot have a great effect on improving the patient's vision. They have the necessary expertise to perform this surgery and are approved by the international ophthalmology community.