Learn about Parkinson's drugs and their side effects and complications Parkinson's is known as a progressive neurological disease and disorder that changes the movement and coordination of the body.... The probability of contracting this disease increases with age.... The process of this disease is progressing after diagnosis and if the symptoms are not controlled, it gradually worsens.... The cause of this disease is the loss of brain cells that are responsible for the production of a type of dopalls neurotransmit medicine.. Parkinson's disease... We will, so stay with us until the end.... ### Introduction of Parkinson's disease As we said, Parkinson's disease is caused by the destruction of dopamine cells, but the exact cause of this problem is not known.. But based on the evidence, the possibility of Parkinson's disease is related to heredity.. In fact, those who have had Parkinson's disease in their family are more at risk of developing this disease. Depression and anxiety... - balance problems (increasing the possibility of falling) - loss of sense of smell (anosmia) - Spitting - Sleep problems - Speech disorder - Memory problems For more information, see the Parkinson's disease article.... ### Parkinson's treatment methods Regarding the treatment of Parkinson's disease, it should be said that, unfortunately, no method has been introduced to treat this disease, and treatment methods are followed with the aim of controlling Parkinson's disease and preventing its progression... Among these treatment methods, we can mention the use of Parkinson's drugs and tablets, which we will discuss in detail in the following article... For Parkinson's, in addition to drug therapy, physical treatments such as physiotherapy and rehabilitation are also used, which are effective in improving the patient's movement abilities.... Medicines Parkinson's.. The most important thing you should know about the types of Parkinson's pills is that all Parkinson's drugs must be taken with a doctor's prescription and exactly according to the doctor's order.... Avoid any change in the dose of the drug or change the time of taking the Parkinson's drug separately... Stay with us as we introduce these drugs.... Levodopa and Carbidopa can be considered the most important drugs for Parkinson's disease.. Levodopa is a drug that travels from the digestive system to the brain and is converted into dopamine there. Today, to increase the effect and reduce the need for a high dose, carbidopa is also used alongside it.. The decrease in dopamine is somehow replaced and the motor symptoms caused by the disease are reduced.. - Abnormal and uncoordinated movements (dyskinesia) - Abdominal pain - Nausea - Dizziness - Confusion - Change in heart rate - Changes in blood pressure ##### Carbidopa-levodopa drug interaction Carbidopa-levodopa, also known as Sinemet, may interact with the following drugs: MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobamide, phenelzine, procarbazine, tranylcypromine) - Bromopride - Chlorogyline - Furazolidone - Iproniazid - Nialamid - Pargillin - Sulpiride ### 2.... Dopamine agonists This drug group does not convert into dopamine in the brain, but it has the same effect and is used to compensate for the lack of dopamine. Dopamine agonists, which are usually prescribed in the early stages of the disease, reduce the patient's motor symptoms, but their effect is less than levodopa... The following can be mentioned from this drug group: - Pramipexole - Ropinirole - Apomorphine - Rotigotine ##### Side effects of dopamine agonists Among the side effects of taking this group of Parkinson's pills, the following can be mentioned: - Drowsiness - Disruption of voluntary movements - Illusion - Swelling or discoloration of the leg - Compulsive behaviors ##### Drug interactions of dopamine agonists Before prescribing this group of drugs, inform your doctor about all the drugs you are taking.... Dopamine agonists may interact with various drugs that vary according to the prescribed pills and include various.... Note that the use of this group of Parkinson's drugs is prohibited for women during pregnancy and breastfeeding... ### 3... MAO-B inhibitor This group of drugs prevent the breakdown of dopamine in the brain... Monoamine oxidase type B enzyme or MAO-B is an enzyme that breaks down dopamine... By taking MAO-B inhibitor drugs, the amount of MAO-B enzyme production decreases and dopamine remains in the brain... These drugs are used in the early stages of the disease... Among the drugs in this group, the following can be mentioned: - Selegiline - Rasagiline - Sefin Amid ##### Side effects of MAO-B inhibitors Taking this group of judges as Parkinson's pills may have the following side effects: - - Nausea - Constipation - Dizziness - Confusion - Illusion - Dry mouth ##### Drug interaction of MAO-B inhibitors Among the drugs that interact with MAO-B inhibitors, the following can be mentioned: Droperidol or prochloroprazine - Granistrone - Ondansetron - Linezolid - Methyl thionium chloride (methylene blue) - Ciprofloxacin ### 4.... COMT inhibitors This group of drugs is prescribed as an adjunctive treatment with levodopa. The enzyme catechol-O-methyltransferase (COMT) is known to inactivate levodopa and reduce the effect of the drug. From the drugs... From the drugs of this group, the following can be mentioned: - Entakapone - Tolkapon - Epicapon #### Side effects of COMT inhibitors The use of COMT inhibitor drugs, like other types of Parkinson's pills, may be associated with the following side effects: - Voluntary movement disorder - Confusion - Illusion - Change in color of urine - Diarrhea #### Drug interactions of COMT inhibitors It is necessary to check the patient's medications before prescribing any type of COMT inhibitor. Among the drugs that interact with COMT inhibitors, the following can be mentioned: - - Apomorphine - Bitoltrol - Cholestyramine - Dobutamine - Epinephrine - Isotarin - Isoproterenol - Methyl dopa - Probencid - Antibiotics ### 5.... Amantadine Alternative text: amantadine tablets It is said that amantadine can help reduce tremors caused by Parkinson's disease by affecting brain receptors.. This drug was initially known as an antiviral drug, but today it is among the drugs that are also effective in reducing movement problems. Of course, the exact way this drug works for Parkinson's disease is not exactly known. Amantadine is also used alone or in combination with other drugs such as levodopa. The effects of taking amantadine as a Parkinson's pill can be considered as follows: - - Low blood pressure - Dizziness - Illusion - Nausea - Sleep problems - Confusion - Foot color change ##### Amantadine drug interaction As with any Parkinson's drug used by patients, amantadine also interacts with certain drugs as follows: central nervous system stimulants (dextroamphetamine, atomoxetine and methylphenidate) - Anticholinergic drugs (diphenhydramine, scopolamine, tolterodine and benztropine) - Cardiac drugs (Triamterene-Hydrochlorothiazide) - Malaria drugs (quinine and quinidine) - Flu vaccine ### 6 .... anticholinergic Anticholinergics are prescribed with the aim of reducing involuntary muscle contractions and tremors in the treatment of Parkinson's... This group of drugs has a quick effect and helps reduce abnormal contractions and oral secretions... This group of Parkinson's drugs is most effective in young patients who experience the early symptoms of Parkinson's. - Benzotropin (Cogentin) - Trihexyphenidyl ##### Side effects of anticholinergics Some people may experience the following side effects by taking this group of Parkinson's pills: - Dry mouth - Confusion - Illusion - Decreased memory - Blurred vision ##### Drug interactions of anticholinergics There is also a possibility of drug interaction in the group of anticholinergic drugs and includes the following: Antidepressants (amitriptyline, nortriptyline, paroxetine, fluoxetine and monoamine oxidase inhibitors or MAOIs) - Antihistamines used to treat asthma, hay fever and hives Acetylcholinesterase inhibitors - Tiotropium, ipratropium bromide and potassium chloride tablets ### 7... Istradfilin (Noryan) Alternative text: Parkinson's treatment Istrafeline belongs to the group of adenosine A2a antagonist drugs. This drug is administered along with levadopa and can improve the patient's motor function... The exact way this drug works is not known, but it is said to manipulate the receptor responsible for slowing down movements in the brain. Among other side effects of this drug, it can be mentioned that patients increase the sensitivity of dopamine receptors. Parkinson's drug: - Voluntary movement disorder - Dizziness - Insomnia - Illusion ##### Drug interactions of Estradafilin Estradaphylline interacts with various drugs, some of which are: - - Alstrent - Rifamycins (rifabutin and rifampin) - Medicines to treat seizures (carbamazepine and phenytoin) - Smoking reduces the effect of this drug.. In this article from Dr. Kihani Fard's website, we have introduced the types of Parkinson's drugs and introduced you to the drug information of each one... Don't forget that prescribing, taking, changing the dose and changing the time of taking Parkinson's drugs is possible only with the doctor's order... Before starting the period of taking the drug, consider all the doctor's recommendations and then carefully read the instructions on the drug package.. parkinson.org health line nhs.uk webmd mayoclinic.org