داروهای ضد افسردگی عموما برای درمان انواع مشکلات مربوط به حوزه سلامت روان به ویژه افسردگی و کاهش میزان اضطراب، استفاده میشوند. By affecting brain chemicals known as neurotransmitters, these drugs will be effective in improving mood and reducing symptoms of depression and anxiety.
But on the other hand, there are concerns about side effects of antidepressants and in this article from Dr. Kihani Fard's clinic, we intend to thoroughly examine these side effects and provide you with ways to reduce them. Stay with us until the end.
How do antidepressants work?
According to the documents provided on the medical website Rx List Common antidepressants by changing the balance of brain chemicals known as neurotransmitters, symptoms such as moodiness, lack of desire for things that people used to enjoy and will cure the lack of energy. In people with depression, brain cells do not have access to these types of chemical messengers in sufficient numbers; Therefore, antidepressants will increase the access of brain cells to these types of cases.
What are the side effects of antidepressants?
In order to better understand the side effects of taking antidepressants, it is better to have a detailed look at all the side effects of various drug groups in this field. Therefore, this grouping will be as follows:
Side effects of SSRI and SNRI antidepressants
according to the definitions provided on the medical website American Psychiatric Association This group includes specific serotonin reuptake inhibitors and norepinephrine serotonin reuptake inhibitors, and their side effects include From:
- Feeling excessively shaky, anxious or agitated;
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- Indigestion and stomach pain
- Face with diarrhea and constipation;
- Decreasing appetite in people;
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- Insomnia or feeling sleepy from my drugs;
- decrease in libido;
- Difficulty reaching orgasm during sex;
- Facing erectile dysfunction.
- Indigestion and stomach pain
Keep in mind that the mentioned cases may have similarities with other drug groups.
Side effects of TCAs tricyclic antidepressants
The common side effects of this category are as follows:
- dry mouth;
- lightly blurred vision;
- weight gain;
- Increased body sweating, especially at night;
- Rapid heartbeat or fast heartbeat.
These types of side effects should decrease naturally after a few weeks as your body gets used to the medication.

Are all those who use these drugs exposed to its side effects?
Using different types of antidepressants may have different side effects. But these side effects are not the same for all people and it depends on the type of medicine, dosage and duration of use. Some drugs have more side effects and higher doses are usually associated with more side effects.
Also, some side effects of taking antidepressants may appear at the beginning of treatment and decrease with time. Individual medical conditions also play an important role in this field. People with underlying medical conditions may be more prone to side effects. In addition, drug interactions can also increase the risk of complications.
For this reason, the use of antidepressants must be done under the supervision of a specialist doctor in order to minimize their side effects as much as possible and achieve the best results.
Short-term side effects of antidepressants
Some of the most important side effects of taking antidepressants in the short term are as follows:
- nausea;
- fatigue and sleepiness or frequent insomnia;
- Severe Headaches;
- weight gain;
- Decreased libido;
- dry mouth;
- face with dizziness;
- increasing the amount of sweating;
- Feeling anxiety and worry;
- Changes in appetite;
- muscle pains;
- occurrence of digestive problems;
- Heartbeat;
- Feeling of numbness or tingling in the muscles.
But these short-term side effects usually appear at the beginning of treatment and may disappear with time.
Long-term effects of taking antidepressants
The long-term side effects of using antidepressants are as follows:
- significant increase in body weight;
- incidence of sexual disorders;
- feeling of chronic fatigue;
- occurrence of memory and concentration problems;
- Increased risk of type 2 diabetes;
- Changes in blood pressure;
- increasing the possibility of heart diseases;
- suffering from drug withdrawal syndrome;
- Changes in people's mood;
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- decreasing quality of life;
- Feeling dull or lethargic;
- Increased risk of some cancers;
- Chronic sleep disorders.
This is why it is always important to use antidepressants under the supervision of doctors specializing in this field.
The interaction of antidepressants with other drugs and their effects
In order to investigate this discussion, it is necessary to first know that the use of antidepressants interferes with the use of other drugs. These drugs are as follows:
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- Antihypertensive drugs;
- antifungal drugs such as fluconazole;
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- anticonvulsant drugs;
- some herbal medicines like St. John's wort;
- hypnotics.
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But drug interactions with the mentioned items can cause serious effects on people's health. These effects will be as follows:
- Decreasing the effectiveness of the drug: Some drugs can reduce the effectiveness of antidepressants;
- Increasing the level of medicine in the body: Drug interactions may increase the amount of medicine in the blood and bring the risk of poisoning the body;
- Changes in metabolism: Some drugs can change the metabolism of antidepressants;
- Creating effects on blood pressure: Some drugs can raise and lower blood pressure;
- Changes in sleep: inside antidepressants with other drugs can affect your sleep pattern;
- significant decrease or increase in appetite: Some drug interactions can affect appetite;
- Changes in mental status: drug interaction affects the mood and mental status of people.
According to the mentioned cases, we insist that the medicines must be used under the supervision of a doctor and with his advice, so that steps can be taken to reduce side effects.
How can the side effects of antidepressants be reduced?
To reduce the side effects of antidepressants, it will be necessary to consult a doctor first. The doctor may adjust the dosage of the drug or use an alternative drug. Also, starting treatment with a low dose and gradually increasing it can help reduce side effects.
On the other hand, following a balanced diet and increasing physical activity can also have a positive effect on reducing side effects. Keeping the body hydrated and consuming enough fluids will also help reduce dry mouth and digestive problems. Also keep in mind that the use of some stress management techniques such as meditation and yoga will be very useful to improve the mental state and reduce the side effects of antidepressants.
Conclusion
The use of antidepressants has always been associated with some side effects. Therefore, people are looking for a way to reduce the amount of these side effects, and in this article, from the center of the clinic Dr. Kihani Fard, we tried to investigate better and more side effects of taking antidepressants and provide you with solutions to control the amount of side effects, in this direction. Dear ones, let's help. We hope that the contents are useful and efficient. Thank you for being with us until the end.