Repata ampoule is usually prescribed in patients who have not responded well to dietary or oral methods to control blood fat levels and reduce high cholesterol. Repata helps prevent cardiovascular diseases by reducing the level of LDL or bad cholesterol in the blood. The effect of this drug is usually seen a few weeks after starting the treatment. Regular use and follow-up of the treatment course is necessary to achieve the desired result. Complete information about how to use, side effects and drug interactions is important for the patient. In the continuation of this article from your doctor, all the details related to Repata ampoule are provided.
What is Repata ampoule and what is its use?
Repata ampoule is an injectable drug that belongs to the class of PCSK9 inhibitor drugs. This drug reduces the risk of cardiovascular diseases by reducing bad cholesterol in the blood. Repata is usually prescribed in patients with familial hypercholesterolemia or refractory to treatment with oral medications. This medicine must be taken under the supervision of a doctor and according to the specified dosage to have a proper effect.
Regular consumption and follow-up of blood tests to check cholesterol levels are very important. Repata is usually supplied in the form of ready-to-inject ampoules and needs to be stored in the refrigerator. The effect of this drug is gradual and it may take a few weeks to see changes in cholesterol levels and blood fat.
Drug ID
Description
What is Repata Ampoule?
Repata Ampoule reduces the risk of cardiovascular diseases by reducing cholesterol.
Generic Name Drug
Evolocumab
Brand name
Repatha
Type of drug
Biological drug / monoclonal antibody
Chemical formula
IgG2 protein with approximate formula: C₆₂4₂H₉648N₁668O₁996S₅6 (human antibody)
Pregnancy classification
in Australia B1; In America, it does not have a specific classic FDA classification, but according to the guidelines, it should be used only if there is a clinical need.
Half-life
Estimated about 11 to 17 days
Drug elimination
Mainly through proteolytic and target-oriented pathways; Kidney/liver does not play a major role.
Mechanism of action
Inhibition of PCSK9 protein, which usually reduces LDL receptors in the liver; By inhibiting PCSK9, the number of LDL receptors is increased and LDL (“bad”) cholesterol is cleared from the blood more. Refrigerator temperature is usually suitable.
How to use
Subcutaneous (injection under the skin) in the abdomen, thigh or arm with a pre-filled pen or syringe.
Drug Form
Injectable solution in prefilled syringe/pen 140 mg/mL and injection systems 420 mg
Similar drugs
Other PCSK9 inhibitors such as alirocumab (brand name Praluent)
Information The birth certificate of Repata drug is as follows.
English text: Repatha is a brand-name drug that comes as a liquid solution for injection under the skin. It's prescribed for high cholesterol. Persian translation: Repata is a brand drug that is supplied as a subcutaneous injection solution. This drug is prescribed for the treatment and control of high cholesterol.
Repata is specifically designed to lower the level of LDL, or bad cholesterol, in the blood and can help reduce the risk of heart disease related to blood fat.
How to inject Repata ampoule
Injection of Repata ampoule is usually done subcutaneously in areas such as thigh, abdomen or arm. Before injection, the target area should be cleaned and disinfected to prevent infection. The ampoule should be injected according to the doctor's order and using the appropriate syringe and needle.
After the injection, gentle pressure on the injection site for a few minutes can prevent pain and swelling. The patient can self-inject this drug, but proper training by a doctor or nurse is necessary. It is very important to store the medicine at the right temperature and away from direct sunlight.
Best time to inject Repata Ampoule
Repata injection is usually given every two weeks or every four weeks depending on the doctor's prescription. It is better to inject at a certain and regular time so that the drug level in the blood remains stable. Choosing the injection time should be done according to the patient's daily schedule and the doctor's order. Some patients prefer to do the injection in the morning or in the evening to manage it more easily. It is very important to write down the date of injection and observe the intervals between doses. It is not recommended to change the injection time without consulting a doctor.
Uses of Repata Ampoule
Repata ampoule is prescribed to reduce LDL cholesterol levels in patients with familial hypercholesterolemia or resistant to oral medications. This medicine is also used in people who have heart or vascular diseases and need strict control of cholesterol.
Repata can help reduce the risk of heart attack, heart attack, and other complications from high cholesterol. It is recommended to use it in combination with a healthy diet and exercise. This drug is usually prescribed for patients who have not been able to reach the therapeutic goal with statins. The doctor may adjust the dose and intervals of the injection based on the individual's condition.
Repata ampule dosage
The usual dose of Repata ampoule is determined depending on the severity of the disease and the doctor's recommendation. The standard dose is usually 140 mg every two weeks or 420 mg every four weeks. The doctor may adjust the dose based on the patient's response to treatment and LDL level. Arbitrarily changing the dose or injection interval can reduce the effectiveness of the drug. Accurately observing the timing of the injection is very important to maintain the drug level in the blood.
Repata ampule side effects
Side effects of Repata are usually mild and include pain, redness, or swelling at the injection site. Some patients may experience symptoms such as headache, fatigue, or mild gastrointestinal symptoms. A severe allergic reaction or sensitivity to the drug is rare, but a doctor should be consulted immediately if respiratory symptoms or severe swelling occur.
Muscle or joint pain may also occur in some people. Many side effects decrease with continued treatment and there is no need to stop the medication. Regular reporting of complications helps the doctor to continue the treatment more safely.
English text: Repatha can cause serious side effects including serious allergic reactions. Stop taking Repatha and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms. Persian translation: Repatha can cause serious side effects, including severe allergic reactions. Stop taking Repatha immediately and call your doctor or go to the emergency room if you experience symptoms such as difficulty breathing or swallowing, skin rashes (hives), rash or itching, and swelling of the face, lips, tongue, throat, or arms. noopener">repatha
Drug interaction of Repata ampule
Before starting the treatment, you should tell your doctor about all the medicines and supplements you are taking. Repata usually has no significant drug interactions and can be used together with statins. The doctor determines the injection schedule based on the medical history and medications. Patients should avoid taking new medications without consulting a doctor. It is important to report any sudden changes in medications to avoid interactions. Compliance with instructions and medical follow-up helps reduce the risk of interference.
Repata ampule contraindications
People who are allergic to any of the components of the drug should not use Repata Ampoule. Concomitant use with certain cardiac or bleeding medications may cause restrictions.
Children and teenagers are usually treated with a doctor's opinion. Also, people who have a history of severe allergic reactions should be careful. Before prescribing, the doctor performs the necessary tests to confirm the safety of the drug.
Use of Repata-Ampoule during pregnancy and breastfeeding
Adequate information about the safety of Repata during pregnancy is limited and should be used only if necessary and with the advice of a doctor. During breastfeeding, it is recommended to take the drug under the supervision of a doctor to avoid transfer to breast milk. The benefits and risks of drug use should be discussed by the doctor with the patient. In case of any unusual complications or symptoms, inform the doctor immediately. If possible, the doctor may postpone the use of the medicine until after pregnancy or the end of breastfeeding.
Injection of Repata ampoule is usually done subcutaneously in areas such as thigh, abdomen or arm.
Repata drug information table
Important and key drug information of Repata ampoule is presented in a table so that you can easily review the features, dosage, side effects and storage tips of this drug. This table helps the patient and his caregivers to use Repata safely and effectively.
Drug names
Side effects
Interactions
Repata 140 mg ampoule
Injection site pain or redness
May interact with statins or anticoagulants
Repata Ampoule 420 mg
Headache
–
–
Fatigue
–
–
Mild gastrointestinal symptoms
–
In this table, the medicinal information of Repata is stated.
Repata ampoule price
The price of Repata ampoule varies depending on the place of purchase, dose and number of packages. The drug is usually covered by special insurances or support programs. It is important to buy from reputable pharmacies and follow the doctor's prescription. Comparing prices and finding out about discounts can reduce treatment costs. Proper storage of the drug and its timely use will reduce the additional cost due to the wastage of the drug. The patient should consult a doctor or pharmacist before purchasing to determine the dosage and duration of use.
Conclusion
Repata Ampoule is an effective drug to reduce LDL cholesterol and prevent heart diseases. Regular consumption, follow-up of doses, and adherence to injection and storage instructions are necessary for the drug to be effective. Awareness of side effects and drug interactions helps in safe use. The drug should be taken under the supervision of a doctor and with the control of sugar, blood pressure and proper diet. Overall, Repata can be an effective option for patients who do not respond to oral therapies.
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Frequently Asked Questions
Repata Ampoule is suitable for people with high cholesterol or familial hypercholesterolemia and adequate response to oral medications have not given Also, patients with a history of heart or vascular disease who need a drastic reduction of LDL can benefit from this medicine.
Using Repata is usually safe, but side effects such as injection site pain, headache, and fatigue may occur. Patients should report any unusual symptoms or allergies to their doctor so that treatment can continue safely.
Yes, Repata is specifically designed to lower LDL or bad cholesterol levels in the blood and can Help reduce the risk of heart diseases related to blood fat. This drug is especially suitable for people who have not responded to oral drugs.
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