The best drops to reduce eye pressure [14 powerful drugs + administration method]

Daria Radmanesh List of disorders and diseases Eye Last updated: 2 days ago Published: 7 days ago No question

Pending review by Darmankade medical team

As we examined in the article What is eye pressure and what are its symptoms; Eye pressure is the pressure that the internal fluid of the eye exerts on the wall and structure of the eye, and its existence is necessary to maintain the spherical shape of the eye and the proper functioning of the optic nerve. But when the eye pressure becomes excessive, the risk of glaucoma increases and if not diagnosed and treated in time, it can seriously damage the optic nerve. In such a situation, eye drops are used as the first line of treatment for high eye pressure. The best drop to reduce eye pressure should be chosen by an ophthalmologist based on the severity of the disease, the age of the patient and underlying conditions. In this article from Darmankade Health Magazine, join us to introduce you to the best eye pressure drop.

Table of Contents

• What is eye pressure drop?
• drop Suitable for improving eye pressure
  • 1- Prostaglandin analogs
  • 2- Blockers Beta
  • 3- agonists Alpha
  • 5- Rho kinase inhibitors
  • 6- Eye drops Combined
• Eye pressure drop effects
  • eye pressure and Cetirizine
• Frequently Asked Questions

What are eye pressure drops?

Eye pressure drops It is prescribed to reduce intraocular pressure and its main role is to treat diseases such as glaucoma and lowering eye pressure. Intraocular pressure rises when the balance between the production and drainage of aqueous humor (it creates eye pressure and is regularly produced and drained in the eye) is disrupted. This condition can seriously damage the optic nerve. Eye drops are used as the first line of treatment in most patients with the aim of preventing this damage and preserving vision.

Actually, the best drops to reduce eye pressure, which we will introduce in full in the next section, depending on the type of drug, lowers eye pressure by reducing fluid production in the ciliary body or increasing fluid drainage from the natural pathways of the eye.

Choosing the type of eye pressure drops is very important along with lifestyle modification and paying attention to foods useful for eye pressure and should be done depending on factors such as intraocular pressure, type of glaucoma, age of the patient, underlying diseases and how the person responds to treatment. Also remember, correct and regular use of eye drops under the supervision of the best eye doctor in Tehran is very important Because glaucoma can progress silently, and in such a situation, irreversible complications can only be prevented by continuously controlling the eye pressure. prevent the condition from worsening.”

Eye drops are a common treatment to help manage glaucoma. Although they do not improve vision, they can prevent it from getting worse. Glaucoma eye drops usually work by helping to drain fluid from the eye or by reducing the amount of fluid that the eye produces. This helps to reduce the pressure in the eye and prevent the situation from worsening.
Quoted from the site: medicalnewstoday

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Suitable drops to improve eye pressure

Drops to reduce eye pressure should be used with the direct prescription of an ophthalmologist.

Eye pressure reduction drops have several different categories that are prescribed by an ophthalmologist. The doctor usually prescribes the best drops for eye pressure treatment based on the type of glaucoma, severity of eye pressure, patient's age, underlying diseases and how the patient responds to treatment. The classification and best eye drops for lowering eye pressure include the following:

1- Prostaglandin analogs

Eye drops containing prostaglandin are the main drops for high eye pressure and are usually considered as the first line of treatment for open-angle glaucoma. By increasing the outflow of aqueous humor from the uveosacral path, this drop helps to reduce intraocular pressure and prevent damage to the optic nerve. The best eye drops for reducing eye pressure of prostaglandin analogs include the following:

• Latanoprost eye pressure drop (one of the most widely used eye drops for glaucoma treatment, which has a strong effect in reducing eye pressure.)
• Bimatoprost eye pressure drop (its effect is stronger than latanoprost and in addition to the uveosacral route, It also affects the trabecular path.)
• Travoprost eye pressure drop (has the same effect as latanoprost and facilitates the outflow of aqueous humor.)
• Tafluprost eye pressure drop (used for patients who have open-angle glaucoma or eye pressure treatment with other drops is not suitable for them.)
• External eye pressure drop Latanoprosten Bonaud (This eye drop releases nitric oxide and relaxes the trabecular meshwork; for this reason, it is useful for draining fluid and reducing eye pressure.

Method of use: This medication is usually prescribed once a day. Remember that eye drops containing prostaglandins are known as refrigerated eye pressure drops; It means that before opening, they should be kept in the refrigerator at a temperature of 2 to 8 degrees Celsius. After opening, you can store them at room temperature and away from direct sunlight.

Possible side effects: Possible side effects of eye pressure drops containing prostaglandin may include a feeling of something in the eye, blurred vision, redness or eye pain, eye color change, and an increase in the number, thickness, and length of eyelashes.

2- Beta blockers are the best eye drops to reduce eye pressure and prevent glaucoma. By reducing the production of aqueous humor in the ciliary body, the aqueous humor in the eye is largely influenced by beta-adrenergic receptors receptors, prevent excessive production of fluid and reduce intraocular pressure. The most common beta blockers are: Timolol eye pressure drops (a common medication that helps reduce intraocular pressure caused by open-angle glaucoma or other diseases associated with high eye pressure.)

Betaxolol eye pressure drops (to reduce pressure in chronic angle glaucoma) It is effective again.)

Method of use: The doctor usually prescribes drops of this category for 1 to 2 times a day.

Possible side effects: Despite the therapeutic benefits, beta blockers can cause systemic side effects; therefore, patients with asthma, heart disease, uncontrolled diabetes, or low blood pressure should use them with caution Redness or burning of the eyes, blurred vision and symptoms of low blood sugar, stop using beta-blocking eye drops and inform the doctor.

3-Alpha agonists

Alpha agonists are a class of eye pressure-reducing drops that work with a dual mechanism, which means that they both reduce the production of aqueous humor in the eye and increase its outflow. Drops of this category, which include brimonidine and opraclonidine, reduce intraocular pressure by stimulating alpha-2 receptors in the ciliary body; Therefore, the doctor may prescribe them to treat glaucoma.

Method of use: Usually, the doctor recommends that you put one drop in the affected eye 3 times a day, approximately 8 hours apart.

Possible side effects: You may experience things like burning, blurred vision, redness and itching of the eyes, headache, and a drop in blood pressure.

4- Inhibitors Carbonic anhydrase

Damage to the optic nerve can be prevented with the correct and regular use of drops to reduce eye pressure. Carbonic anhydrase inhibitor eye drops are known as the best eye drops for high eye pressure and glaucoma. These drops reduce the production of aqueous humor by inhibiting the activity of the carbonic anhydrase enzyme in the ciliary body and are useful for reducing eye pressure. The enzyme carbonic anhydrase plays an important role in the production of aqueous humor. The use of carbonic anhydrase inhibitor drops reduces fluid production and brings eye pressure to a safe level. The most common drops in this category include the following:

• Dorzolamide eye drops (This eye drop is prescribed alone or together with timolol to reduce eye pressure.)
• Brinzolamide eye drops (This eye drop is effective in reducing eye pressure and has better eye tolerance than dorzolamide.)

Method of use: The doctor usually recommends using carbonic anhydrase inhibitor drops twice a day, morning and night.

Possible side effects: It may cause side effects such as burning eyes, a bitter taste in the mouth, or temporary blurred vision.

5-Rho kinase inhibitors

In the list of the best drops to reduce eye pressure, you should include eye drops Let's mention Ripasodil from the group of Rho kinase inhibitors. By increasing the outflow of aqueous humor from the trabecular path, this drop helps to reduce eye pressure in patients with glaucoma or high eye pressure. Rho kinase inhibitors act by affecting a specific enzyme pathway that plays an important role in controlling eye pressure and facilitate the drainage of aqueous humor from the eye and bringing the eye pressure to a safe level. Method of use: It is usually recommended to use this eye drop once and often in the evening. Possible side effects: Some people may experience side effects such as eye redness, burning, corneal deposits and Mild spot bleeding in the white of the eye.

6- Combined eye drops

Combined eye drops contain 2 or more active ingredients that are prescribed to patients with glaucoma or high eye pressure. These drops simultaneously help lower eye pressure by reducing the production of aqueous humor and increasing its drainage. Choosing the best combined drops to reduce eye pressure should be done based on individual conditions and under the supervision of an ophthalmologist in order to achieve the desired result and reduce the risk of side effects. The most common combined eye drops are:

• Xylomol eye pressure drop containing 2 drugs timolol and dorzolamide
• Cozopet eye pressure drop containing 2 drugs dorzolamide and timolol

Other common combinations that may be prescribed by an ophthalmologist include brimonidine-timolol, brimonidine-brinzolamide and travoprost-timolol mentioned. These compounds are considered a safe and effective option for reducing eye pressure in patients who have not responded sufficiently to single-component drops. Of course, you should only use combined drops under the supervision of an ophthalmologist. Important: If you suffer from high eye pressure, take regular follow-up and visiting an ophthalmologist to check the symptoms and adjust the dose of eye pressure drops. For this purpose, you can also use online ophthalmology examination.

In the table below, we have summarized the types of eye pressure drops, the mechanism of action and the side effects of each one:

Drug className of the eye dropMechanism of actionPossible side effects Prostaglandins Halatanoprost, Bimatoprost, Travoprost, Tafluprost Increased outflow of aqueous humor Presence of something in the eye, blurriness Vision, redness or eye pain, change in eye color and increase in the number, thickness and length of eyelashes Blockers beta timolol, betaxolol, reduction in the production of aqueous humor, redness or burning of the eyes, blurring of vision, alphabrimonidine agonists, opraclonidine, reduction in the production of aqueous humor and increasing its exit from the eye, burning sensation, blurring of vision, redness and itching of the eyes, headache and lowering of blood pressure Carbonic inhibitors Anhydrazorzolamide, brinzolamide, reduction of aqueous humor production, burning of the eyes, bitter taste in the mouth or temporary blurring of vision, Rho kinase inhibitors, pasodil, increased outflow of aqueous humor, redness of the eye, burning, corneal deposits, and mild spot bleeding in the whites of the eyes. Temporary table of drops to reduce eye pressure

Complications of eye pressure drops

The best drop to reduce eye pressure despite many therapeutic benefits, may cause a series of side effects. The most common possible side effects of eye pressure drops include the following:

• Eye redness
• Eye burning
• Temporary blurred vision
• Eye itching

In some special cases, patients may experience side effects such as dry eyes, sensitivity to light, or the feeling of a foreign body in the eye. Rare side effects of eye drops to reduce eye pressure include breathing disorders, heart rate changes and damage to the retina. To reduce the possibility of any side effects, it is better to use eye pressure drops under the supervision of an ophthalmologist and monitor side effects seriously. Also, knowing what foods increase eye pressure reduces the risk of developing eye pressure and the need to use eye drops As a result, the patient is not exposed to the side effects of eye pressure drops.

Eye pressure and cetirizine

If you have a history of eye disease or are taking certain medications, consult your doctor before using eye pressure reduction drops.

Some experts believe that increased eye pressure and temporary blurring of vision can be side effects of Cetirizine. Cetirizine is one of the widely used antihistamines for the prevention and treatment of allergic reactions. Antihistamines may increase intraocular pressure due to their mild anticholinergic effects. Of course, Cetirizine is a second-generation antihistamine, which has much lower anticholinergic properties compared to the first-generation drugs. However, it is better for people who use the best drops to reduce eye pressure or have a history of eye disease to consult with their ophthalmologist before long-term use of cetirizine to avoid drug interactions.

How to use the best drops to reduce eye pressure

To use drops to reduce eye pressure, just follow the following steps:

• First, wash your hands with soap and water to prevent the transfer of germs to the eyes.
• To be in the right position, bend your head slightly back and look up.
• Pull the lower eyelid down slowly with your finger to create a hole-like space for the drop to enter.
• Drop the prescribed number of drops into the hole. Gently press the inner corner of the eye (next to the nose) with your finger so that the medicine does not enter the tear duct.
• After finishing, close the drop cap tightly and place it somewhere away from direct sunlight.

Guide to see a doctor

Choosing the best drop to reduce eye pressure depends on various factors such as the type of glaucoma, the level of eye pressure, the general condition of the person and how the patient responds to the medicine. Currently, there are several categories of eye pressure drops, each with a different mechanism of action, such as reducing the production of aqueous humor or increasing its output, which helps to lower eye pressure and treat glaucoma. If you have more questions about their safety and effectiveness according to your specific conditions, you can visit the website Dharmankade and consult the best specialist doctors such as an ophthalmologist. Also, the clinic has provided you with the possibility of receiving an online appointment for face-to-face consultation or online consultation by phone, text and video.

Frequently asked questions

What should I do if I forget to use a dose of eye pressure drops?

If you forget to use a dose of eye pressure reduction drops, take it as soon as you remember; Unless the next dose is close. Remember to never use 2 drops at the same time to make up for a missed dose.

How long does it take for the best drop to reduce eye pressure to work?

Usually eye pressure reducing drops are fast-acting and start lowering eye pressure a few hours after the first use. But the lasting effect and complete treatment with eye pressure drops may take several weeks.

What is the best eye pressure drop?

Choosing the best eye pressure drop should be done by an ophthalmologist. Depending on the severity of the eye pressure and the individual's condition, the doctor usually chooses one of the categories of eye drops suitable for high eye pressure, such as prostaglandins, beta blockers, alpha agonists, carbonic anhydrase inhibitors, Rho kinase inhibitors or combined eye drops.

Sources: medicalnewstoday | glaucoma | nweyeclinic

Top doctors: Dr. Abdul Samad Mehdizadeh | Doctor Syed Mohammad Reza Hosseini Firouzabadi | Doctor Mehdi Khatami

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