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What is the gut microbiome and why is it important? - Dr. Mohammad Amani, specialist in gastroenterology and liver
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What is the gut microbiome and why is it important? - Dr. Mohammad Amani, specialist in gastroenterology and liver

3 weeks ago
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Dr. Mohammad Amani

Dr. Mohammad Amani

Tehran

Adult gastroenterology and liver specialist

میکروبیوم روده چیست و چرا اهمیت دارد؟

مدت زمان مطالعه 9 دقیقه

میکروبیوم روده یکی از مهم‌ترین بخش‌های بدن است که تا مدت‌ها نادیده گرفته می‌شد. درون روده ما میلیاردها میکروب مفید زندگی می‌کنند که مانند یک تیم پنهان، به هضم غذا، تقویت سیستم ایمنی، تنظیم وزن و حتی تعادل روحی ما کمک می‌کنند. New research shows that the health of this microscopic population plays a decisive role in the prevention of many digestive and general diseases. For this reason, knowing the intestinal microbiome and ways to maintain its balance has become one of the main topics in the world of medicine and health today.

What is the intestinal microbiome?

Intestinal microbiome refers to a huge collection of microorganisms that live in the digestive system, especially the large intestine. This collection includes bacteria, viruses, fungi and other useful microbes, each of which has a specific role in the health of the body. The number of these microbes is so high that it is estimated that their number is several times the number of cells in the human body.

Intestinal microbiome acts like a complex biological system; That is, just as every part of the body has a task, each group of these microorganisms also plays a role in food digestion, production of some vitamins, regulation of immunity and even influence on mood. The existence of balance in this microscopic ecosystem is necessary to maintain the health of the body; Because when this balance is disturbed, the possibility of problems such as bloating, inflammation, weak immune system, digestive problems and even mood changes increases. In simple words, the gut microbiome is the population of beneficial microbes whose presence is absolutely necessary for the proper functioning of the body.

What does the gut microbiome consist of?

The gut microbiome is a huge collection of microorganisms that includes bacteria, viruses, fungi, yeasts and archaea, and each one has a unique role in maintaining the health of the gut and the body. The largest share is made up of bacteria that help digest food, produce vitamins and protect against pathogens. Viruses, especially bacteriophages, play a role in controlling the bacterial population, and fungi and yeasts also contribute to the balance of intestinal ecology. This diverse collection, together with their genetic material, creates a complex and dynamic ecosystem that has a wide influence on the immune system, metabolism and even brain function.

What does the gut microbiome do?

The gut microbiome is a collection of beneficial microorganisms that perform a wide range of vital functions in the body. gives This microbial community helps in digesting and breaking down food, makes vitamins such as B and K and plays an important role in strengthening the immune system. The intestinal microbiome prevents the growth of harmful microbes and prevents inflammations and digestive diseases by maintaining the balance in the intestine. In addition, by producing chemical messengers and affecting the gut-brain axis, it plays a role in mood, anxiety and even brain function. It is also effective in regulating weight, metabolism, blood sugar levels and skin health and is considered an active and intelligent organ in the body.

Why is the gut microbiome important?

The gut microbiome is important because it plays many vital roles in maintaining the health of the body and actually acts like a hidden but very active organ. does This microbial complex helps digest food, absorb nutrients and produce vitamins and plays a key role in strengthening the immune system. The microbiome maintains the intestinal balance and prevents the growth of pathogenic microbes. In addition, it affects mood, stress, sleep and even cognitive function through the gut-brain axis. Microbiome health is directly related to weight, metabolism, diabetes, inflammation, skin health and even autoimmune diseases. For this reason, any imbalance in the microbiome can lead to serious problems such as digestive disorders, obesity, depression, and immune disorders.

Intestinal microbiome in the digestive system

Intestinal microbiome in the digestive system has a fundamental and multi-layered role, and without it the digestion process cannot be carried out completely. Beneficial gut microbes help break down foods that the human body cannot digest on its own, such as fiber and complex carbohydrates. The result of this breakdown is the production of short-chain fatty acids that provide energy to intestinal cells and reduce inflammation. The microbiome also helps better absorption of minerals such as calcium, magnesium and iron and plays a role in the production of vitamins such as K and B. In addition, by competing with harmful microbes, it keeps the intestinal environment safe and prevents problems such as bloating, diarrhea, constipation and inflammation. In short, the gut microbiome is one of the main pillars of digestive system health.

How does the gut microbiome help absorb nutrients?

The gut microbiome helps better absorb nutrients by carrying out a series of vital processes. First, the useful intestinal microbes break down fibers and complex carbohydrates, which the human body is unable to digest directly, and turn them into short chain fatty acids; These acids strengthen the health of intestinal cells and improve the absorption of nutrients. Some bacteria also play a role in the breakdown of fats and proteins, making the intestine better able to absorb amino acids and fatty acids. In addition, the microbiome facilitates their absorption by increasing the bioavailability of minerals such as calcium, magnesium and iron. The production of essential vitamins such as K and B by bacteria also helps to complete metabolic processes. The sum of these functions makes the intestinal microbiome one of the key factors in the efficiency of the digestive system and the absorption of nutrients.

How does the intestinal microbiome prevent digestive problems?

Intestinal microbiome plays an important role in digestive health by maintaining a delicate balance between beneficial and harmful bacteria. This microbial complex prevents many digestive problems by controlling the intestinal environment, strengthening the intestinal barrier and supporting the immune system. When this balance is maintained, food digestion is better, inflammation is reduced, and the possibility of bloating, constipation, diarrhea, and intestinal disorders is significantly reduced. Harmful

  • Adjusting intestinal pH and creating an unsuitable environment for dangerous microbes
  • Strengthening the intestinal barrier and preventing the leakage of harmful substances (intestinal leakage)
  • Reducing intestinal inflammation by producing short-chain fatty acids
  • ✅ Improving bowel movement and preventing constipation, bloating and diarrhea
  • regulating immune reactions and preventing disorders such as IBS
  • supporting better digestion and preventing the accumulation of undigested substances that cause digestive problems
  • In general, the health of the gut microbiome is one of the main foundations of the proper functioning of the digestive system. When the balance of these microbes is maintained, the gut works at its best and the body is protected against inflammation, infection and digestive disorders. Strengthening the microbiome with healthy nutrition, fiber consumption, probiotics and the right lifestyle can play an important role in preventing digestive problems and improving the quality of life. In fact, taking care of the gut microbiome means taking care of the whole body.

    What environmental factors affect your gut microbiome?

    The gut microbiome is strongly influenced by environmental factors, and these factors can strengthen or weaken the composition, diversity and function of beneficial gut microbes. Any change in lifestyle, nutrition, or environmental conditions can cause or disrupt the microbial balance, thereby affecting digestive health, immunity, metabolism, and even mood. Knowing these factors helps to create an environment suitable for the growth of beneficial microbes and a better functioning of the digestive system through conscious choices.

    • Diet: The type of foods we consume, especially the amount of fiber, sugar, fat and processed foods—have the greatest impact on the composition of the microbiome.
    • Use of antibiotics: Antibiotics can destroy both harmful and beneficial bacteria and disturb the balance of the gut.
    • Stress and anxiety: Chronic stress through the gut-brain axis causes changes in microbial activity and diversity.
    • Insufficient sleep: Lack of sleep or sleep disorder can disrupt the composition of the microbiome.
    • Activity Physical: Regular exercise increases the diversity of the microbiome and helps improve gut function. Environmental: Living in urban, rural, polluted, or natural environments can each change the way the body is exposed to microbes. Exposure to chemicals: Air pollutants, detergents, and food preservatives can interact with the microbiome.
    • Method of birth and infant feeding: Natural childbirth and breastfeeding can create the foundation of a healthier microbiome.
    • Smoking and alcohol: Both can significantly change the composition of bacteria.
    • Age: As we age, the diversity and function of the microbiome also change.

    Recognizing and managing the environmental factors that affect the gut microbiome can play an important role in maintaining the overall health of the body. By making simple changes such as improving nutrition, reducing stress, regular physical activity and avoiding the excessive use of drugs, conditions can be created for beneficial microbes to grow and intestinal function to be in the best possible state. In fact, taking care of the gut microbiome means strengthening a powerful support system that affects everything from digestion to immunity and mood.

    Methods to maintain and improve the gut microbiome

    Maintaining and improving the gut microbiome requires simultaneous attention to nutrition, lifestyle, and daily habits. Beneficial gut microbes can only perform at their best when they receive the right nutrients and live in a balanced, stress-free environment. By making a few simple but effective changes in your diet and daily behaviors, you can strengthen the microbial balance and improve your digestive health, immunity and even your mood. Essential

  • ✅ Stress management and care of the gut and brain axis
  • ✅ Regular exercise
  • ✅ Sufficient and regular sleep
  • ✅ Keeping the body hydrated
  • ✅ Reducing alcohol and quitting smoking
  • ✅ More food variety
  • Creating and maintaining a healthy gut microbiome requires continuity and conscious choices in everyday life. By following proper nutritional principles, reducing stress, regular physical activity and avoiding harmful habits, an ideal environment for the growth of beneficial microbes can be provided. The result of these efforts will be improved digestion, strengthening of the immune system, increased energy and even better mood. In fact, paying attention to the gut microbiome is an effective investment for the long-term health of the whole body.

    Summary

    Ultimately, the gut microbiome is not just a complex scientific topic, but an integral part of our everyday health; From food digestion and absorption of nutrients to regulation of body immunity, weight, mood and even sleep quality. Every food choice, every sleepless night, and every period of stress can throw this delicate ecosystem out of balance or out of balance. If we learn to eat more mindfully, manage our stress, and be more mindful of taking medications, especially antibiotics, we are actually investing in the health of our gut microbiome and thus the long-term health of our entire body. Taking care of the gut microbiome is a serious and smart step towards a healthier, more energetic and balanced life.

    Frequently Asked Questions

    Does food affect the gut microbiome?

    Yes, diet, especially fiber consumption and fermented foods, directly changes the composition of the microbiome.

    Do antibiotics destroy the microbiome?

    Yes, antibiotics kill both bad and good bacteria and disrupt the gut balance.

    How can I strengthen my gut microbiome?

    By consuming high-fiber foods, probiotics, stress reduction, exercise, and adequate sleep.

    Does stress affect the gut microbiome?

    Yes, stress can disrupt the microbial balance and cause digestive problems.

    What are the signs that the gut microbiome is not healthy?

    Bloating, constipation, diarrhea, fatigue, skin problems and mood changes are common symptoms.

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