If your doctor has recently prescribed this medication for you, stay with us in the next article from GCORP LLC health magazine to introduce you to the uses, side effects and how to take medroxyprogesterone.

What is medroxyprogesterone?

This drug, which is prescribed in the form of tablets or ampoules, is a hormonal drug from the progesterone category and is considered a type of synthetic progesterone... Progesterone is one of the natural hormones of the female body that is produced by the ovaries and plays an important role in the proper functioning and health of the female reproductive system... The balance of this hormone in the female body regulates the menstrual cycle and maintains pregnancy...

Medroxyprogesterone is one of the drugs that is prescribed when the hormonal balance of progesterone is disturbed.... Medroxyprogesterone is widely used to treat common problems of women related to hormonal imbalance..

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The mechanism of action of medroxyprogesterone

The mechanism of action of this drug is similar to the action of the natural progesterone hormone in the body....This drug exerts its biological effects by binding to progesterone receptors in the target tissues....for example, by increasing the level of progesterone hormone, the luteal phase is strengthened and with its sudden decrease, endometrial tissue shedding occurs. It inhibits the release of gonadotropin hormones from the pituitary gland, which prevents ovulation...

The mechanism of action of medroxyprogesterone in the treatment of disorders caused by increased estrogen, such as abnormal bleeding or endometrial hyperplasia, is that it prevents the stimulating effects of estrogen by reducing the effect of estrogen on uterine tissue.

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Medroxyprogesterone drug use

The most important uses of this pill are:

• Setting the menstrual cycle
• Treatment of premenstrual syndrome such as breast pain and swelling, depression, tension and mood changes
• Treatment of polycystic ovary syndrome
• Treatment of amenorrhea
• Prevention of abnormal growth of the lining of the uterus
• control of some types of cancer such as breast and uterine cancer
• Treatment of menopause symptoms such as hot flashes

Other uses of medroxyprogesterone include:

Medroxyprogesterone and the possibility of pregnancy

One of the main uses of this drug is to regulate menstruation.. In fact, by regulating the menstrual cycle, medroxyprogesterone tablets can indirectly cause ovulation, which helps to increase the probability of pregnancy.

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Medroxyprogesterone to stop bleeding

This pill is one of the effective drugs in controlling and stopping abnormal uterine bleeding, which usually occurs due to hormonal imbalance or dysfunction of the endometrium. Medroxyprogesterone after the period aims to regulate the hormones of the menstrual cycle and repair the endometrial layer and reduce bleeding, thereby reducing isorosis or reducing bleeding in the uterus... In many cases, the bleeding decreases within a few days after starting the drug, and menstruation starts three to seven days after stopping the drug.

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Medroxyprogesterone and contraception

Medroxyprogesterone Acetate pill or injectable form, which is usually prescribed at a higher dose, is used to prevent pregnancy... the right doses of this drug suppress ovulation by reducing the secretion of FSH and LH hormones and prevent the entry of sperm by changing the cervical mucus..

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Medroxyprogesterone for ovarian cysts

This pill is prescribed for ovarian cysts when the cysts are caused by a hormonal imbalance. Synthetic progesterone medication does not directly eliminate the cyst, but by regulating hormones, it can help prevent the formation of new cysts and reduce the symptoms of ovarian cysts.

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How to use medroxyprogesterone

You must take this medicine completely according to the doctor's order.. because the dose can be different from one person to another.... The doctor determines the appropriate amount and dose of the medicine based on the reason for the prescription, the severity of the symptoms, the general state of the person's health and how the body responds to the treatment...

Medroxyprogesterone 10 mg is usually prescribed for the treatment of amenorrhea and uterine bleeding in women with polycystic ovary syndrome who do not intend to get pregnant... this dose of medicine should be taken 10 to 14 days a month.. The way to take medroxyprogesterone tablets is a little different... The doctor usually recommends using this pill from the 16th to the 21st day of the menstrual cycle after the start of the last period.

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Among other important points in taking different doses of this drug, the following can be mentioned:

• Take the medicine completely until the end of the treatment period.
• Dose of medicine is determined by your doctor based on your body's needs.. Therefore, avoid changing or stopping it arbitrarily.
• You can take the medicine with or without food.
• If you have digestive problems, it is better to take the pill with food.
• This medicine should be swallowed with a full glass of water...so avoid crushing, breaking or chewing it.
• If you miss a dose, take the missed dose as soon as you remember. However, if the next dose is close (less than four hours), you can skip the missed dose and continue taking the pill as directed by your doctor.

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The best time to take medroxyprogesterone

The duration of taking this medicine depends on the prescription and the medical condition of the person.. On the other hand, considering that the dose of medicine can be different for each person, it is better to consult the doctor about the time of use.. In general, in response to people who ask when is the best time to take medroxyprogesterone, it can be said that you should take this medicine at a certain time every day so that a constant dose of it remains in the body.

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Medroxyprogesterone precautions and contraindications

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This pill should be used with caution in the presence of the following conditions and diseases and may be contraindicated in some cases:

• sensitivity to medicinal compounds
History of blood pressure, diabetes, asthma and migraine Cardiovascular diseases such as heart failure, irregular heartbeat and heart attack Liver and kidney problems
• History of abortion
• Blood coagulation disorder
History of breast, uterine and ovarian cancer
• Convulsions or epilepsy
Porphyria disease History of depression High cholesterol and triglycerides
• Eating disorder
• osteoporosis

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Medroxyprogesterone pill in pregnancy and breastfeeding

Usually, the use of this drug is not recommended during pregnancy, except in special circumstances that the doctor deems necessary... Because this drug can increase risks such as birth defects in the stages of fetal development... But at the discretion of the doctor, an appropriate dose of this drug may be prescribed to prevent repeated abortions or to support pregnancy in the early stages and to use IUI..

Currently, the use of medroxyprogesterone in breastfeeding is not approved, because there have not been enough studies on the transfer of the components of this drug through breast milk to the baby and possible side effects... Although some hormonal drugs It affects the amount of milk secretion and the child's behavior, but if it is necessary to use this medicine, the doctor will decide on its use during breastfeeding.

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Medroxyprogesterone side effects

This pill, like other drugs, may have a series of side effects, which include:

• Headache and dizziness
• Pain and swelling of the breasts
• Change in the pattern and intensity of the course
• Delpiche
• Excitability
• Depression and anxiety
• weight gain
• Acne, hair loss and skin rashes
• Vaginitis and urinary infection
• Digestive problems such as bloating, nausea, heartache, vomiting, diarrhea or constipation
• Drowsiness
• Extreme fatigue and physical weakness
• Increase or decrease in blood pressure
• Bronchitis, sinusitis and pharyngitis
• Hot flushes, loss of libido and heavy menstrual bleeding
• Back pain and joints

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Medroxyprogesterone drug interaction

Drug interactions can reduce the effectiveness of this pill or increase the possibility of side effects.. Medicines that may interact with this pill include:

• Antidepressants such as fluoxetine, sertraline, venlafaxine and bupropion
• anticonvulsant drugs such as phenytoin, carbamazepine and lamotrigine
Anticoagulants such as warfarin and heparin
• anti-ovulatory drugs such as danazol and clomiphene
• Antiviral drugs such as ritonavir and indinavir
Benzodiazepines such as alprazolam, diazepam
• Zopiclone and Zalplon
Levothyroxine and other thyroid medications
• Amphetamine, duloxetine and multivitamin
Ciprofloxacin, diphenhydramine and cetirizine

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What is the difference between medroxyprogesterone and duphaston?

Medroxyprogesterone and Duphaston are both synthetic progestins that have similar functions and mechanisms.... The difference between these two drugs can be seen in their side effects.... Medroxyprogesterone tablets have more side effects and Duphaston tablets cause fewer side effects due to better body tolerance.... The choice between these 2 drugs should be made according to the conditions of the doctor and the patient.>

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Guide to see a doctor

Medroxyprogesterone is one of the important hormonal drugs whose mechanism of action is based on the natural progesterone hormone in the body.. This drug is prescribed to regulate the menstrual cycle, treat abnormal uterine bleeding, control menopausal symptoms and prevent endometrial thickness..

Although this drug plays an essential role in the treatment of many problems related to women's periods and sexual health, it should not be used without the direct prescription of a specialist doctor.. because it can cause side effects such as spotting, body fluid retention, mood changes and increased risk of blood clots...

In this article from GCORP LLC magazine, we talked in detail about the application, side effects and method of taking medroxyprogesterone tablets.... If you have more questions about the safety and effectiveness of this drug according to your specific conditions, you can visit the GCORP LLC website and consult the best online doctors.. Obstetricians and Gynecologists.... Also, GCORP LLC has provided you with the possibility to make an appointment with the doctor of your choice through the online appointment system in order to visit the gynecologist in person.

Frequently Asked Questions

Forums related to this article

• How many days after progesterone injection will I have my period?

Sources: webmd | medscape