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Learn about amyloidosis and its treatment
مقاله تخصصی

Learn about amyloidosis and its treatment

3 months ago
321 بازدید

Amyloidosis disease is a rare complication, during this disease, a type of abnormal protein called amyloid is created in some organs of the body....Amyloid disrupts the function of any organ that is created.

Of course, it should be noted that amyloid is not created by itself in the body, but its structure is a combination of several proteins in the body. As a result, amyloidosis is created under certain conditions.

Amyloidosis affects which organs the most?

In some people, amyloidosis occurs along with other diseases.

However, the treatment prescribed for this disease, depending on the cause of its occurrence, can include amputation of the affected limb, chemotherapy, drug therapy, organ transplantation or bone marrow and stem cell transplantation.

Although amyloidosis may affect any organ in the body, it most commonly affects the heart, kidney, liver, spleen, digestive system, and nervous system.

Read more: the cause of Down syndrome in the fetus

What is the cause of amyloidosis?

The cause of amyloidosis disease depends on various factors.... In some people, genetic and hereditary factors lead to the occurrence of this disease.... But in other people, it occurs due to long-term dialysis or untreated inflammation.

In the following, we will introduce you to the types of this disease according to the cause of its occurrence:

1) Amyloidosis AL

AL or primary amyloidosis is actually the most common type of this disease... This type of disease is also known as immunoglobulin light chain amyloidosis... In this type of disease, the heart, kidney, liver and nervous system are usually affected.

2) AmyloidosisAA

AA amyloidosis is also known as secondary amyloidosis.. Because inflammatory diseases such as rheumatoid arthritis are their main cause.

Therefore, controlling inflammatory diseases can greatly reduce the symptoms related to amyloidosis caused by them.. Usually, in people with secondary amyloidosis, kidney, liver and spleen are more involved.

3) Hereditary amyloidosis

As its name suggests, this type of amyloidosis can have a genetic basis.... In these people, an abnormal protein is usually created by the liver.... For this reason, the nerves, heart and kidneys are affected.

In this type of disease, the disorder caused in different organs of the body is due to the presence of trestric protein or TTR.

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4) Wild amyloidosis

Although it may seem strange, but in wild-type amyloidosis, the TTR protein made by the liver is normal.... But for unknown reasons, after a certain period of time, after this protein is produced in the body, amyloidosis occurs..

5) Localized amyloidosis

This type of amyloidosis usually affects different organs and organs. In localized amyloidosis, the bladder, skin, throat or lungs are more vulnerable than other organs.

In general, the most important thing in the field of amyloidosis is timely diagnosis and choosing the correct treatment method... because otherwise, the person may face irreparable consequences.

What factors increase the possibility of amyloidosis?

Although there is a possibility of occurrence of amyloidosis disease like many other diseases in different people, but in total there are factors that increase the probability of occurrence of this disease... These factors are:

  • family background
  • age
  • Gender
  • They suffer from infectious and inflammatory diseases Kidney dialysis
  • Race

What are the symptoms of amyloidosis?

Symptoms of amyloidosis generally depend on the organs affected by this disease... but in some cases, this disease occurs without any symptoms and in a silent state... Unfortunately, in these people, the golden time of treatment may be lost.

In general, the occurrence of amyloidosis is associated with the following signs and symptoms:

  • Irregular heartbeat (may be decreasing or increasing)
  • Wrist or leg swelling
  • Difficulty swallowing or painful swallowing
  • Feeling weak
  • Severe and unusual body fatigue
  • pressure drop
  • shortness of breath
  • bloody diarrhea
  • Constipation
  • Abnormal weight loss
  • Skin spots around the eyes
  • Skin sensitivity
  • Bruise for no reason
  • roughening of the skin
  • Increase the language size
  • Change in shape at the edge of the tongue
  • Nausea
  • Tingling feeling in hands and feet
  • Carpal tunnel syndrome

How is amyloid disease diagnosed?

Given that the symptoms of amyloidosis can be similar to some other diseases, so in many cases the diagnosis based on the symptoms cannot be very accurate and definitive... Therefore, doing a blood test, urine test, imaging or sampling can reduce the risk of wrong diagnosis.

It is necessary to explain that to increase the accuracy of the diagnosis, liver and thyroid function are usually checked in the blood test... The samples taken are often taken from the fat under the skin of the abdomen, bone marrow or damaged organs such as the liver or kidney.

How is amyloid treatment done?

Amyloidosis disease, like many inflammatory diseases, has no specific treatment.. Therefore, all available treatment methods for this disease are only aimed at controlling the symptoms and preventing their progression.

On the other hand, as previously mentioned, if amyloidosis is caused by other underlying diseases such as rheumatoid arthritis or tuberculosis, treating or controlling this underlying disease will also be effective in improving the symptoms of amyloidosis.

In the following, we will share with you dear ones a list of treatments available in the field of amyloidosis improvement:

  • Chemotherapy
  • Pharmaceutical treatment with heart and kidney drugs
  • Blood stem cell transplant
  • Dialysis
  • Member Link
  • Amputation of the injured limb in order to prevent involvement of other organs

Conclusion

In this article, we discussed some points about amyloidosis... Knowing this information can play an effective role in visiting the doctor on time and preventing the irreversible consequences of this disease.

If you or someone close to you is struggling with symptoms similar to amyloid disease, it is better to see a specialist as soon as possible for advice and testing.

Accessing the information of many specialist doctors and booking an appointment with them is easily possible through the GCORP LLC website.

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