The main purpose of PGD is to identify genetic and chromosomal abnormalities, including determining the sex of the embryo, before transferring it to the mother's womb. With this, only healthy embryos with the desired conditions are transferred to the uterus. This method is especially useful for couples who have a history of genetic diseases or need to determine gender for medical reasons.

Sex determination with PGD is done in several clear and precise steps and is usually done at the same time as in vitro fertilization (IVF). The general process of this method is as follows:

First, using special drugs, the ovaries are stimulated to produce several mature eggs. Then the eggs are removed from the ovary and combined with sperm in the laboratory to form an embryo. After a few days, when the embryos reach the appropriate stage of development, one or more cells from each embryo are safely removed. These cells are examined genetically to determine their sex chromosomes.

In the next step, embryos that have the desired gender and are genetically healthy are selected. Finally, the selected embryo is transferred to the mother's uterus to form a pregnancy. Due to the direct examination of the genetic structure of the fetus, this method is very accurate in determining gender and is considered one of the most reliable methods available.

Fetal gender selection before pregnancy Using gender determination with PGD is a scientific and accurate method that enables an informed and safe decision by genetic examination of the fetus.

How successful is gender determination with PGD?

The success rate of gender determination with PGD method is very high and close to certainty. In terms of sex detection, the accuracy of this method is usually reported to be more than 99%, because the sex of the fetus is determined based on the direct examination of sex chromosomes (X and Y).

But it should be noted that the final success is not limited to gender determination with PGD. Factors such as mother's age, egg and sperm quality, fetal health, uterine condition and the skill of the treatment center are influential in the success of pregnancy. For this reason, the sex of the fetus may be chosen correctly, but the pregnancy does not lead to the birth of a baby.

In short, PGD is very accurate and reliable in terms of sex selection and diagnosis, but the chance of a successful pregnancy depends on various medical factors.

PDG method risks

• Damage to the embryo: One of the possible risks is very minor damage to the embryo at the time of cell harvesting. Although this probability is low, in rare cases it can affect the development of the fetus.
• Interpretation error: Among other things, laboratory error is very rare in the interpretation of genetic results. The advancement of technology has made these errors to be minimized, but they are not zero.
• Complications of Fertility Methods: The PGD procedure is usually done in conjunction with IVF, so there are risks associated with IVF, such as complications from ovarian stimulation drugs, pain, bloating, or a very small chance of ovarian hyperstimulation syndrome (OHSS).
• Emotional damage: It may also be psychologically stressful for couples, especially if the number of healthy or desired-sex embryos is limited.

It should be mentioned the high cost and unavailability of this method in all medical centers. For this reason, PGD should be done after careful consultation with a specialist doctor and examination of individual conditions.

If you are looking for the best obstetrician and pregnancy consultation, you can get a free consultation from Dr. Mahshid Karimi.

PGD and PGS difference

Determining gender with PGD and PGS depends on the purpose and type of genetic testing, although both are performed in conjunction with IVF.

PGD (pre-implantation genetic diagnosis)

In this method, the fetus is checked for a specific genetic disease. It is usually used when a parent is a carrier of a known hereditary disease, such as thalassemia or certain sex-linked diseases. PGD ​​performs targeted screening and focuses on a specific gene or chromosome. Gender determination is usually done in the same way.

PGS (pre-implantation genetic screening)

In the PGS method, the aim is to check the overall state of the embryo's chromosomes. This method seeks to identify embryos with an abnormal number of chromosomes (such as Down syndrome) and is used more to increase the chances of a successful pregnancy and reduce miscarriage, rather than to investigate a specific disease.

Generally:

• PGD is used to diagnose a specific genetic disease or determine sex.
  
• PGS is used to check the overall chromosomal health of the fetus.
  
• Targeted and more specific PGD focuses on a specific problem, while PGS has a general screening mode.

best sex determination doctor with PGD

Choosing a specialist doctor plays a very important role in the success of the PGD sex determination method, because this process requires specialized knowledge, practical experience and high precision in assisted reproductive treatments. Among the doctors active in this field, Dr. Mahshid Karimi is known as one of the reliable and well-known options in the field of infertility and PGD gender determination.
He is a surgeon and specialist in gynecology, childbirth and infertility, and by using modern IVF and PGD methods, he provides accurate diagnostic and treatment services to couples. Clinical experience, scientific approach and attention to the individual conditions of each couple are among the factors that have made Dr. Mahshid Karimi a reliable choice for determining the gender of the fetus.

Fetal gender determination with PGD It is a scientific and advanced solution that guarantees high accuracy and health of the fetus by genetic examination of the fetus.

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