10 powerful painkillers for bone pain [how to use + side effects]

Daria Radmanesh List of articles on diseases Orthopedics Last updated: 3 weeks ago Published: 3 weeks ago No questions

Awaiting review by Darmankade medical team

Bone pain is one of the annoying pains that can be caused by arthritis, osteoporosis, inflammation, injury, nutritional deficiency and vitamin D or calcium. If this pain is severe, the person is not able to do his daily activities. In such situations, most people look for strong painkillers for bone pain. Since there are different types of painkillers and each one has a different mechanism of action or soothing power, choosing a strong and suitable painkiller is not an easy task and should be done under the supervision of a doctor. Join us in this article from Darmankade Health Magazine to introduce you to the best and strongest painkiller for bone pain.

1- Ibuprofen pill (Ibuprofen)
2- Naproxen tablets
3-Diclofenac tablets
4- Acetaminophen
5- Celecoxib tablets
6- Indomethacin tablets
7- Aspirin
8- Piroxicam tablets
9- Tramadol tablets
10- Morphine tablets

Frequently Asked Questions

10 strong pain relievers for bone pain

Medications The first line of treatment for bone pain may vary depending on the underlying disease, the doctor's experience, and the individual's general health. However, most experts believe that non-steroidal anti-inflammatory drugs (NSAIDs) are the best and most effective treatment for joint pain and bone pain because they contain enzymes to block pain and swelling. The dosage of painkillers for bone pain should be determined by a doctor.

In the following, we will introduce you to 10 strong painkillers for bone pain and joint pain:

1- Ibuprofen pill

Ibuprofen is one of the strong painkillers from the group of non-steroidal anti-inflammatory drugs (NSAID) that can help reduce bone pain. Ibuprofen works by inhibiting COX-1 and COX-2 enzymes. These enzymes play an important role in the production of prostaglandins (chemical compounds that are produced in response to inflammation and cause pain, inflammation and fever). By taking ibuprofen, cyclooxygenase enzymes (COX-1 and COX-2) are blocked; In this way, inflammation and bone pain are reduced.

The doctor may prescribe ibuprofen tablets in cases where bone pain is accompanied by ankle swelling, to reduce inflammation and pain. If you are curious to know what is the cause of painless ankle swelling, you can read the article related to it in Darmankade.

Dosage: Ibuprofen is available in different forms and in doses of 200 to 800 milligrams (mg). The doctor recommends the right dose for the person up to 3 times a day.

Possible side effects: Ibuprofen tablets may cause side effects such as constipation, diarrhea, gas or flatulence, dizziness, nervousness and tinnitus. If these symptoms persist, be sure to inform your doctor.

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2- Naproxen tablets

Naproxen is another nonsteroidal anti-inflammatory drug (NSAID) known by the brand name Aleve. This drug has the same function as ibuprofen tablets; This means that by blocking COX-1 and COX-2 enzymes, it prevents the production of prostaglandins; For this reason, it plays an effective role in reducing inflammation and bone pain and joint problems. If severe bone pain is associated with back pain and sciatica, your doctor may prescribe an injection. To learn about these drugs, you can read the article best ampoule for sciatica pain in Dermankade.

Dosage: The doctor usually prescribes a different dose of this pill according to the severity of the pain. Dosage may be 220 to 550 mg every 12 hours for mild to moderate osteoarthritis pain. It is also important that people avoid taking more than 1650 mg per day and do not take the medicine for more than 6 months.

Possible side effects: If you notice side effects such as constipation, gas, excessive thirst, headache, confusion and lightheadedness, drowsiness, burning or tingling in the limbs, cold symptoms, ringing in the ears, and hearing problems, stop taking the medicine and inform the doctor. Advanced, back pain and inflammatory joint pain are prescribed.

Diclofenac is another strong painkiller for bone pain from the class of non-steroidal anti-inflammatory drugs (NSAID). This pill consists of compounds such as diclofenac potassium and can act as an inhibitor of COX-1 and COX-2 enzymes. In fact, diclofenac helps reduce joint and bone pain by inhibiting the secretion of prostaglandins, which are responsible for causing pain and inflammation; For this reason, diclofenac tablets are often prescribed by bone pain doctor to treat and improve bone pain.

Dosage: The doctor usually recommends taking 75 to 150 mg of this tablet for 2 to 3 times a day.

Possible side effects: If side effects like If you experience diarrhea, constipation, dizziness and headache, ringing in the ears, gas and bloating, be sure to inform your doctor.

4- Acetaminophen

Acetaminophen tablet, unlike NSAIDs, does not have a strong anti-inflammatory effect, but because it does not cause digestive discomfort, it is effective for relieving mild to moderate bone pain. This pill helps reduce pain by blocking the activity of COX 3. In fact, acetaminophen tablets are mostly prescribed for people who are allergic to non-steroidal anti-inflammatory drugs due to severe digestive discomfort.

Dosage: Adults can take doses of 325 to 500 mg every 4 to 6 hours, depending on the doctor's recommendation. The appropriate dose of acetaminophen for children must be determined by a doctor.

Possible side effects: Possible side effects of this pill include headache, nausea, and hives. If these side effects, especially in children, do not go away after a few hours, be sure to inform the doctor.

5- Celecoxib

Celecoxib is another non-steroidal anti-inflammatory pill (NSAID) that is known as the best painkiller for bone pain. This pill is specifically a selective cyclooxygenase-2 (COX-2) inhibitor and can reduce pain and inflammation caused by joint and bone problems. In fact, by inhibiting the COX-2 enzyme, celecoxib reduces the production of prostaglandins and reduces pain and inflammation related to bones. Of course, when the intensity of bone pain, especially in the knee, is high and the pills are not effective enough, the doctor may prescribe an injection drug such as the best pain reliever for knee pain.

Dosage: The doctor usually recommends taking a dose of 100 to 200 mg of this drug for one to two times a day.

Possible side effects: This pill may cause side effects such as diarrhea, constipation, nausea, vomiting, respiratory tract infection and heartache in some people. If you experience any of these symptoms continuously, be sure to inform your doctor.

6- Indomethacin

Indomethacin tablets have a strong anti-inflammatory effect and can help reduce bone pain.

Another non-steroidal anti-inflammatory drug (NSAID) pill that helps reduce the pain of joint and bone problems is indomethacin. This pill is considered one of the strong NSAIDs and is usually prescribed when bone pain and inflammation are not controlled by weaker drugs. Indomethacin tablets, like other non-steroidal anti-inflammatory drugs, help to reduce bone pain and joint problems by inhibiting enzymes in the body that cause the release of prostaglandins and the occurrence of pain and inflammation.

Dosage: The doctor usually starts this medicine with a dose of 25 mg for 2 to 3 times a day, and in case of severe pain and according to the individual's conditions, it may be increased to 25 mg a day.

Possible side effects: If you experience side effects such as diarrhea, nausea, heartburn, vomiting, heartache, extreme fatigue, and headache that continue continuously after taking several doses of indomethacin tablets, be sure to inform your doctor.

7- Aspirin

Aspirin is a strong painkiller for bone pain that belongs to the category of drugs Non-Steroidal Anti-Inflammatory (NSAID). This pill inhibits COX-1 and COX-2 enzymes and by reducing the secretion of prostaglandins, it relieves pain and inflammation caused by joint and bone problems. Of course, you should know that aspirin has less anti-inflammatory power than other NSAIDs such as ibuprofen and diclofenac and may not be able to effectively reduce severe bone pain. Dosage: The doctor may prescribe a dose of 325 to 650 mg of this pill every 4 to 6 hours. Possible side effects: Be sure to take aspirin under the supervision of a doctor. Because this pill interacts with many medicines. Its most important possible side effects include digestive discomfort and the risk of stomach bleeding.

8-Piroxicam tablets

Oral piroxicam is one of the non-steroidal anti-inflammatory drugs (NSAID) that is used for the treatment of severe and chronic bone pain, especially bone pain caused by arthritis, back pain, joint wear and inflammation, due to its long-term effect and high anti-inflammatory power Musculoskeletal is prescribed. By inhibiting the production of prostaglandins, this pill can reduce inflammation and relieve bone pain.

Dosage: The doctor usually recommends taking piroxicam tablets once a day due to its long-lasting effect.

Possible side effects: If side effects such as diarrhea, constipation, nausea, tinnitus, dizziness, and heartburn go away after a few days. If not, be sure to inform your doctor.

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9- Tramadol tablets

Tramadol is an opiate-like pain reliever that is used for very severe and unbearable bone pain. This pill should only be obtained with a doctor's prescription. Tramadol is prescribed when conventional medications such as NSAIDs (ibuprofen, naproxen and diclofenac) are not strong enough to control pain. By affecting the pain receptors in the nervous system of the brain, this pill reduces the feeling of pain and is used for pain caused by severe bone damage, fractures, acute back pain or advanced arthritis. Dosage: This pill must be taken under the supervision of a specialist doctor. The doctor usually prescribes it for short-term treatment. Possible side effects: Drowsiness, dizziness, nausea, dry mouth, mood changes and dependence are among the most important side effects of tramadol.

In the list of strong painkillers for bone pain, we should also mention morphine. Oral morphine is considered one of the strongest painkillers for bone pain, which is used only in cases of very severe pain. This drug is a type of narcotic that is obtained from poppy juice and acts as an agonist of opioid receptors in the brain. The doctor may prescribe this pill during severe bone pain or during surgery.

Dosage: This pill should be taken under the full supervision of a doctor; Because if taken arbitrarily, it can cause severe side effects such as nausea, vomiting and breathing problems.

"Pain relievers are among the most commonly prescribed medications to reduce bone pain, but they don't cure the underlying condition. Over-the-counter treatments such as ibuprofen (Advil) or acetaminophen (Tylenol) can be used. Prescription medications such as Paracetamol or morphine may be used for moderate or severe pain."
Analgesics are among the most commonly prescribed medications to relieve bone pain, but they do not treat the underlying disease. Over-the-counter medications such as ibuprofen (Advil) or acetaminophen (Tylenol) can be used. Prescription drugs such as paracetamol or morphine may be prescribed for moderate or severe pain.
Quoted from the site: healthline

Possible side effects: Morphine is highly addictive and its dosage should be determined by a medical professional.

The table below summarizes the best effect of See strong pain reliever pills for bone pain along with their side effects:

Pill NameUsageImportant Side Effects Ibuprofen Reduces mild to moderate bone pain Constipation, Diarrhea, gas or bloating, Dizziness, Nervousness and Tinnitus Naproxen Skin Inflammatory pain in bones and joints Constipation, Gas, Excessive thirst, Headache, Confusion and Lightheadedness, Drowsiness, burning or tingling in the limbs, cold symptoms, ringing in the ears and hearing problems. Acetaminophen. Improvement of mild bone pain without inflammation. Headache, nausea and hives. Diclofenac. Reduction of severe musculoskeletal pain and advanced arthritis. Nausea, vomiting, respiratory tract infection and heartache Indomethacin Severe bone pain or inflammatory joint diseases Diarrhea, nausea, heartburn, vomiting, heartache, extreme fatigue and headache Aspirin Reduction of mild to moderate bone pain Digestive discomfort and risk of stomach bleeding Piroxicam Improvement of severe and chronic bone pain and joint problems Diarrhea, constipation, nausea, tinnitus, dizziness and burning Cold Ultra Modol Skin severe bone pain (if NSAIDs are not effective) Drowsiness, dizziness, nausea, dry mouth, mood changes and morphine dependence, reduction of very severe bone pain, nausea, vomiting, breathing problems and addiction Table of uses and important side effects of strong pain reliever pills for bone pain

What is the best strong pain reliever pill for external bone pain?

Many people are looking for the best external pill to relieve bone pain are In the following, we will introduce you to a strong external pain reliever for bone pain:

Aleve brand name naproxen is a strong external pain reliever for bone pain.
Advil and Motrin brand name ibuprofen can be effective in reducing bone pain.
Voltaren brand name diclofenac is another strong external pain reliever for bone pain, which has long-term effectiveness in relieving severe pain. Bone helps.
External meloxicam (Mobic) pill is effective in relieving bone pain and has few side effects.

Guide to see a doctor

Strong pain reliever pill for bone pain should be chosen based on the severity of the pain, the underlying cause, and the individual's health conditions under the supervision of a specialist doctor. If the bone pain is caused by inflammation, the doctor usually prescribes non-steroidal anti-inflammatory drugs (NSAIDs). In cases where the bone pain is very severe and these pills do not respond well, strong pain relievers such as tramadol or even morphine may be prescribed. However, no medicine is without side effects, so avoid taking it arbitrarily or changing the dose of the medicine without consulting a doctor. If you have any questions about the safety and effectiveness of these tablets according to your specific conditions, you can visit the website Dharmankade and consult the best specialist doctors including Orthopedic Doctor Online. Also, Darmankade has provided you with the possibility to make an appointment with the specialist of your choice through the online appointment system for an in-person orthopedic specialist.

Frequently asked questions

Which pain reliever is best for bone pain?

The best pain reliever for bone pain Pain relievers include non-steroidal anti-inflammatory drugs such as ibuprofen, naproxen, diclofenac, celecoxib, or indomethacin. These drugs help to reduce joint and bone pain by inhibiting the enzymes that secrete prostaglandins, which are responsible for causing pain and inflammation.

Do strong painkillers cure bone pain?

Strong painkillers reduce inflammation and bone pain by inhibiting the enzymes that produce prostaglandins that produce pain, fever and inflammation in response to inflammation, but treat the disease. They are not relevant.

Is it possible to take several strong painkillers together?

Combining several drugs together, unless prescribed directly by a doctor, is very dangerous and can cause serious side effects; So always consult your doctor before combining medications.

Sources: medicalnewstoday | verywellhealth | healthline

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