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Duloxetine tablet and its use: from depression treatment to muscle pain relief
مقاله تخصصی

Duloxetine tablet and its use: from depression treatment to muscle pain relief

3 months ago
797 بازدید

Duloxetine tablet brand name (Cymbalta) is an antidepressant drug from the family of serotonin and norepinephrine reuptake inhibitors (SNRI). This drug, also known as Luxta capsule, is used to treat a wide range of problems such as depression, anxiety and chronic pain due to its effect on the chemical balance of the brain. Because its arbitrary use can have serious side effects.

In this article from health magazine GCORP LLC, join us to check what duloxetine tablets are for treatment, what are the side effects and how to take it.

Table of contents

  • Duloxetine tablet certificate information
  • Duloxetine effect on the brain
  • What is duloxetine tablet for?
  • How to take duloxetine tablet
  • Best time to take duloxetine tablet
  • Duloxetine
    • Duloxetine tablets in pregnancy and breastfeeding
  • Difference between duloxetine tablets and fluoxetine
  • Duloxetine capsule side effects
    • Mild side effects
    • Serious side effects
    • Side effects Gender
    Duloxetine capsule slimming?
  • Duloxetine drug interaction
  • Guide to see a doctor
  • Frequently asked questions

Duloxetine Tablet ID Information

In the table below, you can see the most important medicinal information of this pill:

The effect of duloxetine on the brain

Actually, duloxetine prevents the reabsorption of serotonin and norepinephrine by neurons in nerve synapses.... This inhibition increases the level of the mentioned neurotransmitters in the interneuronal space and strengthens their positive effects on brain function..

Research has shown that this pill can help regulate mood by increasing serotonin and norepinephrine levels, improving depression symptoms such as feeling sad and lethargic, reducing anxiety, increasing energy and relieving fatigue.. On the other hand, duloxetine reduces the sensitivity of the central nervous system to deal with pain by increasing norepinephrine.. Pain... For this reason, this pill is used to control pain and neuropathic pain.. It is prescribed chronically.

Learn more: Diazepam tablets

What is duloxetine pill for?

Learn more: Venlafaxine tablets

The doctor usually prescribes duloxetine 20 tablets and its other doses for the following conditions:

  • Major depressive disorder
  • Generalized anxiety disorder
  • Diabetic peripheral neuropathy
  • Chronic musculoskeletal pain such as joint pain caused by arthritis
  • Chronic muscle pain caused by fibromyalgia

Some research shows that this pill is effective for chemotherapy-induced peripheral nerve damage and stress urinary incontinence in adults, especially men after prostatectomy. Also, some experts prescribe duloxetine 60 mg tablets for chronic back pain in adults.

However, it should be noted that duloxetine is prescribed off-label for the above conditions.. This means that it is not officially approved for the above conditions and the doctor recommends it at his own discretion.

Method of taking Duloxetine tablets

You should take this pill with the doctor's prescription....The doctor determines the dose of the medicine based on the age, weight and severity of the disease for each person....The usual dose of this medicine is once a day, which must be taken orally....To start the treatment of depression, anxiety or pain caused by fibromyalgia, first duloxetine 30 tablets are prescribed and if needed, the amount of medicine is gradually increased to 60 mg..

Important tips when taking Luxta capsules include The following are:

  • You can take this pill with or without food.
  • If you have stomach discomfort, it is better to take duloxetine capsules with food.
  • Use the medicine completely until the end of the treatment period.
  • Duloxetine should be swallowed whole with water. So avoid breaking, crushing or chewing it.
  • Take the pill every day at a certain time so that a constant dose of medicine remains in the body.
  • The doctor starts the treatment with a very low dose and gradually increases it if needed... So avoid changing the drug dose arbitrarily.
  • If you feel better after taking a few doses of the medicine, do not stop it arbitrarily.. because suddenly stopping this medicine can cause side effects.

Learn more: Depakine tablets

The best time to take Duloxetine tablets

Learn more: Difference between fluoxetine and sertraline

The right time to take this pill depends on individual conditions and how the body reacts to the medicine... However, the doctor usually recommends taking Duloxetine capsules in the morning with or after food.... If you feel that taking this pill in the morning makes you sleepy and tired, you can take it at night.

Duloxetine precautions and contraindications

This pill should be used with caution in the presence of the following conditions and diseases... Also, it may be contraindicated in some cases.

  • sensitivity to medicinal compounds
  • High blood pressure
  • Liver problems
  • History of mood and mental disorders such as depression, schizophrenia and bipolar disorder A history of suicidal thoughts and harming yourself or others
  • Overactive thyroid
  • Parkinson's disease
  • Seizure history
  • Diabetes
  • Personal or family history of glaucoma
  • Kidney disease Urinary problems
  • Age over 65 and under 18

Learn more: What are Algomed tablets for?

Duloxetine tablets in pregnancy and breastfeeding

This pill is placed in category C of pregnancy drugs....that is, there have not been enough studies on humans and animals, and research shows that the ingredients of the medicine harm the fetus....So, if you are pregnant or plan to become pregnant, be sure to consult your gynecologist before taking Duloxetine capsules.

It is also not recommended to take Duloxetine tablets during breastfeeding.... Because the ingredients of the drug can be transferred to the baby through breast milk and cause side effects such as irritability, sleepiness and feeding problems for the baby.

Learn more: Phenobarbital tablets

Difference between duloxetine and fluoxetine

Duloxetine and fluoxetine are both drugs that are prescribed to treat mental disorders, but they have significant differences.. For example, duloxetine capsule, in addition to its antidepressant effects, is effective in reducing chronic muscle pain by increasing the level of serotonin and norepinephrine in the brain... A wider range of mood disorders is prescribed..

Capsule side effects Duloxetine

This pill may have side effects like any other drug....we will discuss them below:

Mild effects

Learn more: Trifluprazine tablets

Mild side effects of this pill include the following:

  • dry mouth
  • Nausea
  • Drowsiness
  • Anorexia
  • Constipation
  • dizziness
  • Profuse perspiration
  • Feeling tired
  • Headache
  • Weight loss

Serious side effects

The following symptoms are serious side effects of this pill... If you see any of them, immediately stop taking the medicine and take the patient to the emergency room:

  • Bruising and bleeding
  • Confused thoughts
  • Difficulty sleeping
  • Reckless behavior
  • manic period
  • Excessive energy
  • Excitability
  • Unusual feeling of happiness
  • talkativeness
  • Serotonin syndrome
  • Seizures
  • Severe skin reaction such as erythema multiforme and Stevens-Johnson syndrome
  • Symptoms of liver damage such as yellow skin or severe itching
  • Changes in blood pressure and symptoms such as severe dizziness and fainting
  • Allergic reaction such as skin rash, itching and swelling of the face, tongue, lips and throat

Learn more: Lithium tablets

Sexual effects

Some studies have shown that the use of this pill can be associated with sexual side effects such as the following in men:

  • Erectile dysfunction
  • Difficulty in orgasm
  • Lack of sexual satisfaction

It should be noted that disorders such as depression are associated with sexual complications... so it is difficult to determine whether impotence is one of the side effects of taking duloxetine or a depressive disorder...

Is duloxetine capsule slimming?

Opinions about Duloxetine tablets and weight loss are different... because the effects of this drug on weight can be different in different people.... Some people at the beginning of taking Duloxetine face side effects such as loss of appetite and nausea and lose some weight... while long-term use of this pill can change the body's metabolism and increase weight.

Learn more: Amitriptyline tablets

Duloxetine drug interaction

Drug interactions can reduce the effectiveness of this pill or increase the possibility of side effects.. Drugs that may interact with duloxetine.. They are:
  • Antidepressants such as desipramine, fluoxetine, fluvoxamine and paroxetine
  • Sertraline, Citalopram, S-Citalopram and Dapoxetine
  • Amitriptyline and Clomipramine
  • Venlafaxine
  • Monoamine oxidase inhibitors (MAOIs) such as selegiline and phenelzine
  • Buspirone
  • Warfarin
  • Ibuprofen
  • Indomethacin
  • Ciprofloxacin
  • Lithium
  • triptans
  • Tryptophan
  • Amphetamine

Guide to see a doctor

Duloxetine tablet is a serotonin and norepinephrine reuptake inhibitor drug that helps treat conditions such as major depression, generalized anxiety disorder, diabetic neuropathy, and fibromyalgia. By affecting the chemical balance of the brain, this drug can improve some mental disorders and reduce chronic pain. It is needed...

Find

In this article from GCORP LLC magazine, we talked in detail about the use of duloxetine capsule, its side effects and how to take it... If you have any questions to ensure the safety and effectiveness of the drug according to your specific conditions, you can visit the GCORP LLC website and consult the best specialist doctors, including an online psychiatrist. Also, GCORP LLC has made it possible for you to make an appointment with the psychiatrist of your choice through the online examination system.

Frequently Asked Questions

What is duloxetine pill for?

This pill is prescribed to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, chronic muscle pain, and diabetic neuropathy.

Does duloxetine pill cause weight gain, but it usually causes weight loss? After long-term use due to the effect on the body's metabolism.
What are the side effects of suddenly stopping duloxetine?

Suddenly stopping this pill can be associated with side effects such as anxiety, irritability, difficulty sleeping, extreme fatigue, headacheand nausea..

Sources: webmd | Drugs

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