Allopurinol with the brand name Zyloprim is one of the most widely used drugs for treating gout and controlling the level of uric acid in the body. Also, this drug, which is available in the form of 100 and 300 mg tablets, is used to treat certain types of kidney stones. To check what allopurinol tablets are useful for and how to use them.

What disease is allopurinol used for?

The main use of allopurinol in the body is to reduce the level of uric acid in the blood and to treat gout. In fact, by reducing the production of uric acid, allopurinol prevents the accumulation of uric acid crystals in the joints and tissues. Usually, this drug is not prescribed during acute gout attacks to prevent acute gout attacks..

Other uses of Allopurinol 300 and 100 are as follows:

• This drug is used to prevent the formation of kidney stones caused by high levels of uric acid.
• Another use of this drug is for patients undergoing chemotherapy.... Cancer patients often have high uric acid levels due to the release of uric acid from the diseased cells
• Allopurinol is effective in the treatment of a parasitic disease called leishmaniasis.
• Sometimes, the doctor uses allopurinol 100 or 300 tablets to treat high uric acid caused by psoriasis or diuretics.

Learn more: The most powerful kidney stone removal pill

The mechanism of action of allopurinol

This drug belongs to the category of xanthine oxidase inhibitors and reduces the level of uric acid in the blood.. In fact, allopurinol inhibits the enzyme xanthine oxidase, which is responsible for the production of uric acid in the body, and is very effective in the treatment of gout.

Method of taking allopurinol tablets

This medicine should be taken according to the doctor's order... Usually, the doctor determines the dose of allopurinol based on age, weight, disease severity, medical history, and other medications... Normally, this medicine is prescribed once or twice a day, which should be taken with a full glass of water.

Other important points in taking allopurinol tablets include the following:

• To avoid digestive discomfort, it is better to take allopurinol after food.
• Usually, the effectiveness of this medicine is long, especially in the treatment of gout.. Therefore, it is recommended to take the medicine completely to achieve the desired result.
• It is better to take allopurinol medicine every day at a certain time so that it has a favorable effect.
• The use of this pill starts with a low dose and gradually increases the dose if needed by the doctor.
• Avoid changing the dose of the drug without consulting your doctor or stopping it suddenly.. because this can cause serious side effects.
• If you forget to take a dose of the medicine, take the missed dose as soon as you remember... However, if the next dose is close (less than four hours), you can skip the missed dose and continue taking the medicine as advised by the doctor.
• Although this drug eventually suppresses the attack, it may increase gout attacks during the initial period of treatment. That is why the doctor prescribes colchicine along with it.
• Remember, allopurinol is not a pain reliever and usually the doctor prescribes medicines like ibuprofen or indomethacin to reduce the pain.

The best time to use allopurinol

The best time to take allopurinol 100 tablets and its other doses are usually determined according to the doctor's recommendation and the specific conditions of each patient... However, most experts recommend taking allopurinol after meals to reduce digestive complications.

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Precautions and contraindications of allopurinol drug

This medicine should be used with great caution in the presence of the following conditions or diseases, and it is contraindicated in most cases:

• sensitivity to allopurinol and its compounds
• Diabetes
• Age less than 18 years
Kidney and liver disease
• High blood pressure
• Age over 65 years due to reduced kidney function
• Emergence of symptoms of infection

Allopurinol drug and pregnancy

This drug is placed in category C of pregnancy drugs.... This means that there are currently not enough human studies on its effect on the fetus, and animal research shows serious harm to the fetus.... Therefore, if you are pregnant or planning to become pregnant, be sure to consult your doctor about taking allopurinol tablets during this period.

Allopurinol tablets during breastfeeding

Using this medicine during breastfeeding is not recommended, unless it is directly prescribed by a doctor.. Because there is a possibility of transferring the components of this medicine to the baby through breast milk and it may have a negative effect on the child.

Learn more: What is furosemide tablet for?

What are the side effects of Allopurinol 100 tablets?

Dose 100 and other doses of this pill may cause side effects like any other drug, including the following:

Common side effects of allopurinol

If the following side effects persist for more than a week, be sure to inform your doctor:

• diarrhea
sleepiness
• Digestive discomfort
• Nausea
• joint pain

Rare side effects of allopurinol

If you experience the following side effects after taking allopurinol, stop taking the drug and tell your doctor right away:

• Skin rash
• Painful urination
• Blood in urine
• Fever
Swelling of lips and mouth
• Sore throat
• Weight loss
• Decreased appetite
• Hard breathing
• Jaundice
• Severe tremors and signs of infection

Allopurinol may cause changes in liver function tests, and if left untreated, can lead to liver failure and death... For this reason, it is recommended to have periodic liver enzyme tests while taking allopurinol.

Dangers of overuse of allopurinol

This drug should be taken according to the doctor's prescription.. because its excessive use increases the possibility of the following side effects:

• Constipation
dry mouth restlessness
• Confused
• chest pain
• Skin paleness or change in skin color to blue
• Cough
• Voice change
• Black urine
• muscle cramps
• Decreased memory performance
• Depression

Drug interactions of allopurinol tablets

The simultaneous use of some drugs with allopurinol may cause an interaction in which the effectiveness of the drug decreases or increases the side effects.... Drugs that interact with allopurinol tablets include:

• Ampicillin
• Amoxicillin
• Tolbutamide
• Chlorpropamide
Dicoumarol
• Some gout drugs such as probenecid
• Anticoagulants such as warfarin
• Chemotherapy drugs such as cyclophosphamide
• immunosuppressive drugs such as azathioprine and cyclosporine

Guide to see a doctor

Allopurinol helps to reduce the level of uric acid in the blood and is useful for the treatment of gout.. Also, this drug prevents the formation of uric acid crystals by preventing the formation of certain types of kidney stones.. Allopurinol tablets should be taken under the supervision of a specialist. Usually, the doctor determines the appropriate dose of medicine based on age, weight, and other diseases.

In this article from the GCORP LLC magazine, we examined in detail what allopurinol is for and what side effects its excessive use leads to.... To ask more questions about this drug and consult with the best specialist doctors such as Dr. Rheumatologist, you can visit the GCORP LLC website...

For this, you can visit the website GCORP LLC and consult with the best specialist doctors, including online rheumatology specialist.... GCORP LLC also provides you with the possibility to make an appointment with your desired rheumatology specialist through the online appointment system.. specialist.

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