Mechanism of actionImportant points and considerationsMouth rinsesSalt water, boil SweetGentle cleansing, change oral pHSafe, accessible, must be diluted.Medicated rinsesChlorhexidine 0.12%Disinfectantmay cause tooth discoloration. Prolonged use is not recommended.Coating/preservativesSucralfate suspension, gels containing hydroxypropyl celluloseCreating a physical barrier to zinc WoundPain relief and mechanical protection.Local anestheticsViscous lidocaine 2%Block pain signal transmissionShort-term effect. Risk of involuntary ingestion.Moisturizing productsArtificial saliva, moisturizing spraysSubstitute or stimulate saliva secretionEssential to deal with treatment-induced dry mouth.stimulating factorsPalifermin (Kepivance)factor Keratinocyte growthis used in high-risk cases (stem cell transplant). It is injectable.Natural treatments/complementary medicineManuka honey, aloe vera gelAnti-inflammatory and antioxidant propertyScientific evidence is expanding. It should be coordinated with the attending physician.

reasons The main cause of mouth ulcer after chemotherapy

Chemotherapy is one of the main methods of cancer treatment, but one of its side effects is the occurrence of mouth ulcer. These wounds are caused by different reasons, including damage to fast-acting cells, a decrease in the number of blood cells, and an increase in the possibility of infection. Ulcers usually appear in different areas of the mouth, including the gums, tongue and soft tissue of the mouth, and may cause more pain and problems.

Bacterial and fungal infections of oral ulcers after chemotherapy

The immune system of patients undergoing chemotherapy Treatment is severely weakened. This weakness exposes patients to bacterial and fungal infections. Fungal mouth ulcers are especially common in people taking high doses of immunosuppressive drugs. Symptoms of fungal infections usually include burning and discoloration in the affected area and require medical intervention. Dry mouth and soft tissue inflammation are common side effects that can cause aphthous ulcers in the mouth. For this reason, managing these complications is very important so that the patient can have a better quality of life.

Common and rare oral wounds

Aphthous mouth ulcers and fungal infections are two common types of oral ulcers in chemotherapy patients. These ulcers can usually be identified and treated. But rare mouth ulcers may be caused by allergic reactions or more serious side effects of treatments and require immediate intervention.

Chemotherapy on the immune system and mouth ulcers after chemotherapy and throat

Chemotherapy can significantly affect the immune system. Reducing the number of immune cells and weakening the body's immune response are common side effects of this treatment, which can lead to an increase in the possibility of infection and a delay in the healing of oral and throat wounds. In this way, wounds can lead to varying degrees of pain and inflammation, which makes it difficult to heal. This can lead to painful and inflamed mouth sores in the mouth and throat. Problems such as painful swallowing and lack of nutrition can be other complications caused by wounds.

Inflammation and pain caused by wounds

Inflammation created in wound areas can significantly intensify pain. In cases where patients have mouth ulcers, the severity of the pain causes serious problems in eating and drinking; Therefore, pain and inflammation management should be prioritized.

need for special care in the healing process of oral wound after chemotherapy

Regarding the result of chemotherapy on the immune system and wounds, shows the need for special care strategies makes Doctors must constantly monitor the condition of patients and if necessary, use new and effective treatment methods. id="%D8%A7%D9%87%D9%85%DB%8C%D8%AA_%D9%85%DB%8C%DA%A9%D8%B1%D9%88%D8%A8%DB%8C%D9%88%D 9%85_%D8%AF%D9%87%D8%A7%D9%86_%D8%AF%D8%B1_%D8%AC%D9%84%D9%88%DA%AF%DB%8C%D8%B1%DB%8C_ %D8%A7%D8%B2_%D8%B2%D8%AE%D9%85%E2%80%8C%D9%87%D8%A7%DB%8C_%D9%86%D8%A7%D8%B4%DB%8C_%D Importance Oral microbiome in preventing wounds caused by chemotherapy

The oral microbiome, as an ecosystem of microorganisms, plays an important role in maintaining oral health. Chemotherapy can severely affect this microbiome and lead to serious disorders in oral health. با وجود میکروبیوم سالم، بدن می‌تواند در برابر عفونت‌ها و زخم‌ها مقاومت کند.

نقش میکروبیوم در تقویت سیستم ایمنی

میکروبیوم دهان با تولید مواد ضد باکتریایی به حفظ تعادل میکروبیوم کمک می‌کند و احتمال بروز زخم‌ها را کاهش می‌دهد. Therefore, maintaining the health of the microbiome during chemotherapy is essential.

Effects of chemotherapy on the oral microbiome

Chemotherapy can also damage the healthy cells of the mouth and lead to to reduce microbial diversity. This can aggravate oral ulcers and infections; Therefore, attention to the oral microbiome should be included in treatment plans.

Strategies to maintain the oral microbiome in cancer patients

To maintain the health of the oral microbiome, it is useful to consume probiotics. Also, observing oral hygiene and using non-harmful mouthwashes, avoiding the consumption of sugary and processed foods are other methods that can help. id="%D8%B1%D9%88%D8%B4%E2%80%8C%D9%87%D8%A7%DB%8C_%D9%85%D8%A4%D8%AB%D8%B1_%D8%A 8%D8%B1%D8%A7%DB%8C_%D9%85%D8%AD%D8%A7%D9%81%D8%B8%D8%AA_%D9%88_%D8%A8%D9%87%D8% AF%D8%A7%D8%B4%D8%AA_%D8%AF%D9%87%D8%A7%D9%86_%D8%AF%D8%B1_%D8%AF%D9%88%D8%B1%D9 Methods Effective for protection and oral hygiene during chemotherapy

During chemotherapy, using mild, alcohol-free mouthwashes can help relieve pain and inflammation. These products will help improve oral health because they cause less irritation to sensitive tissues.

proper nutrition for maintaining oral health

Soft foods and less spices help reduce damage to the oral mucosa. Foods such as puree and soup are good options for this period and can be easily swallowed.

Keeping the mouth moist

Consuming enough fluids and using sugar-free sweets are very effective to keep the mouth moist. This action helps prevent dry mouth and improve the patient's quality of life.

importance of oral and dental hygiene in oral wounds after chemotherapy

Brushing with a soft toothbrush and non-irritating toothpaste is another measure that should be taken into account. This helps to maintain the health of the gums and prevent infections.

regular dental examination

Regular dental examinations are very vital during this period. Early detection of problems can help prevent serious complications.

Avoidance of smoking and alcohol

Avoidance of smoking and alcohol also helps the general oral health and speeds up the healing process.

Choosing the right food is extremely important when suffering from oral ulcers. Eating soft foods containing vitamins C and E can help heal wounds and reduce pain.

Avoidance of irritating foods

Eating spicy and hot foods can aggravate pain. It is better to use soft foods to reduce the pain.

The role of hydration in healing wounds

Increasing the consumption of water and liquids leads to maintaining the moisture in the mouth and helps wounds heal faster.

diversity and balance in the diet

Observing variety in the diet and consuming fruits and vegetables helps to strengthen the immune system and accelerate the healing of wounds.

Oral ulcers can be very painful after chemotherapy Pain relievers such as ibuprofen and topical medications such as special gels can help. These drugs should be taken under the supervision of a doctor.

Role of specialized consultation and referring to a doctor for treating wounds

Specialized consultation can help identify the causes of wounds and choose the best treatment methods. This action not only helps to speed up the healing of wounds, but also reduces the risk of infection and side effects. id="%D9%86%D8%AA%DB%8C%D8%AC%D9%87_%DA%AF%DB%8C%D8%B1%DB%8C_%D8%B2%D8%AE%D9%85%E2%80%8C_%D8%AF%D9%87%D8%A7%D9% Result Mouth ulcers after chemotherapy

Mouth ulcers after chemotherapy, awareness and sufficient information about the causes, symptoms and treatment methods are necessary. Observance of oral hygiene, consumption of suitable foods and consultation with specialist doctors can help to improve the quality of life of patients and speed up their treatment process. By adopting these measures, patients can achieve higher degrees of recovery while dealing with the side effects of chemotherapy.

Do all chemotherapy patients get mouth ulcers?

No. Its probability and severity depends on the type of drug, dose, oral health status of the person and genetic factors. By properly preparing the mouth before treatment and strictly following the care instructions, its risk and severity can be significantly reduced.

When do mouth ulcers appear and heal after chemotherapy?

Urses usually appear 5 to 10 days after the start of chemotherapy and reach their peak in the second week. As the treatment cycle ends and the healthy cells regenerate, these sores will gradually heal, usually within 2 to 4 weeks after the treatment cycle ends, provided that a secondary infection does not occur.

Can I use regular mouthwashes for pain relief?

No. It is strongly recommended to avoid alcohol mouthwashes, containing strong disinfectants (such as concentrated hydrogen peroxide) or sodium lauryl sulfate. These substances further irritate and dry the sensitive and damaged mucosa. The best option is a solution of lukewarm salt water (half a teaspoon of salt in a glass of water) or diluted baking soda, unless your dentist or doctor has prescribed a special product.

What if I can't brush because of sores and pain?

Oral hygiene is vital even in these situations, but it should be done more gently. You can:

• Use sterile gauze moistened with salt water to clean the surfaces of teeth and gums.
• Use a super soft baby toothbrush or a special foam toothbrush.
• Rinse the mouth after every meal with a mild solution.
• Be sure to discuss this issue with your treatment team so they can provide a more appropriate solution.

Is a special diet recommended for this period?

Yes. The diet should be soft, nutritious and without stimulants.

• Consumption: pureed foods, thin and cool soups, pudding, yogurt, milk, protein shakes, soft eggs.
• Avoidance: Spicy, acidic foods (such as citrus fruits, tomatoes), salty, crunchy (such as chips, dry bread), hot and alcohol.
• Using a straw to drink fluids can help bypass painful areas.

When should you see a doctor or dentist immediately for a mouth ulcer after chemotherapy?

Contact your healthcare team immediately if you notice any of the following warning signs:

• Fever above 38 degrees Celsius.
• Complete inability to drink liquids.
Active bleeding from the mouth that does not stop
• Severe increase in pain uncontrollable with prescribed painkillers.
• Observing cheesy white lesions (a sign of thrush) or tiny blisters (may be a sign of the herpes virus).

Conclusion

Oral ulcers after chemotherapy are a serious but often manageable challenge. The key to success is active preparation before treatment and continuous care and close collaboration between the patient, family, oncology team and dentist. Ignoring oral health in this way can lead to unnecessary pain, malnutrition, systemic infections and even disruption of the cancer treatment plan.

If you or a loved one is about to start chemotherapy, visiting a dentist who is knowledgeable about these cares is not only a supplementary measure, but an essential part of the cancer treatment protocol. The specialized dental clinic of Dr. Amir Salahjo, understanding the sensitivity of this era, is ready to provide specialized advice, perform necessary preventive treatments and accompany you during the treatment period to maintain oral health and improve the quality of life. 26
Telephone:02144387914
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WhatsApp to book an appointment and free consultation:09106520066
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Contact us today to schedule a pre-chemotherapy consultation and ensure your mouth is ready for this important journey. We are here to help you overcome the disease with more strength.