Table of contents

• Fentanil drug identification information
• Fentanil tablets use
  • 1... Management of sudden pain in cancer patients
  • 2... Anesthesia management and surgical pain control
  • 3... Palliative care donor)
  • How to use fentanyl tablets
  • How to inject fentanyl
  • How to use sublingual and buccal fentanyl tablets
• Calculating the dose of fentanyl
  • 1... dose Fentanyl in anesthesia.... Fentanyl in anesthesia
  • Babies
  • 3... Fentanyl dose in children
  • 4... Fentanyl dose in adults
• Side effects of taking Fentanyl tablets
• Precautions before use or prohibition Use
• Drug Interactions of Fentanyl
• Dise tablets
  • 1... Health problems related to fentanyl in the short term
  • 2... Health problems related to Fentanyl in the long term
• People vulnerable to the drug Fentanyl
• Interactions Drug in the body
• Fentanyl and morphine comparison
• Physician's guide
• Frequently asked questions

Fetanyl drug identification information

You can see the birth certificate information of this drug in the following table:

Use of fentanyl tablets

The main uses of this medicine are:

1.... Management of sudden pain in cancer patients

This drug is usually prescribed to cancer patients who experience sudden and severe pain....These pills are designed to be absorbed quickly and help to provide immediate pain relief....This drug is also usually prescribed to patients who have become resistant to narcotic drugs due to continuous use.

2... Anesthesia management and surgical pain control

Fentanyl is one of the most important drugs for general anesthesia.... Due to its rapid and strong effect, this drug is usually used together with other anesthetic drugs to induce anesthesia before surgery, maintain anesthesia during surgery, and reduce pain during and after surgery.

One of the advantages of this drug for anesthesia is that it reduces the need for other anesthetic drugs and maintains the stability of the patient's cardiovascular system.. Of course, this drug can have a strong effect on the respiratory system.. Therefore, it should be used in controlled environments and by anesthesiologists.

Learn more: What is Perphenazine Tablets?

3.... palliative care

This drug is also prescribed to control the pain of patients who are in the final stages of the disease, especially incurable patients... The main purpose of prescribing this drug is to improve the quality of life of patients through quick and effective pain relief.

How to use Fentanyl drug

When taking this medicine, pay attention to the following points:

• Use this medicine only if prescribed by a doctor and avoid self-administration.
• Read the medication instructions in its box carefully.
• Keep the medicine out of the reach of children and pets.
• This medicine may affect your thinking or reactions.. So, avoid driving or operating machinery until you know how this medicine affects you.
• If you use more than the prescribed dose of this medicine, go to the medical center immediately.
• If you use skin patches and forget a dose, use it as soon as you remember... Do not use extra glue to make up for the missed dose.
• If you use tablets and sublingual spray and miss a dose and there is not much time left until the next dose, do not take the missed dose.
• Use fentanyl only if you have already been treated with similar opioid pain relievers and your body is used to it.
• Take this medicine exactly as directed by your doctor.
• Never take this medicine in larger amounts or more than the prescribed amount.
• Tell your doctor if you feel that you have an increased urge to take fentanyl.

How to use fentanyl tablets

To use the rhombus, follow the steps below:

• Using scissors, open the blister pack (a type of drug packaging) and take out the pill....Do not open the pack until you are ready to take it.
• Place the pill inside the mouth, between the cheek and the gum, using the applicator included in the medicine package... sucking the pill; But do not chew, crush or bite it.
• Move the pill from one side to the other side of the mouth using its applicator so that the medicine is absorbed through the mucosa.
• Do not eat or drink anything while taking the pill.
• If you feel dizzy, sleepy or nauseous before finishing the pill, take it out of your mouth immediately.
• If you use the entire pill, throw the applicator in the trash.
• If you don't finish the pill completely, run the applicator under hot water until all the medicine dissolves... then throw it in the trash out of the reach of children and pets.

Learn more: Gelophane

fentanyl injection method

Fentanyl injection is usually used for pain control and anesthesia. The methods of injecting this drug are:

• Intravenous injection (IV): This method is often used in surgeries to induce and maintain anesthesia.
• Intramuscular injection (IM): In cases where intravenous access is not possible, this drug can be injected intramuscularly.... This method has a delay in the onset of effect compared to intravenous injection.. But it is still effective for pain control.

Remember that the injection of this medicine should be done by health care workers and under the supervision of a doctor.. So avoid injecting it at home.

How to use sublingual and buccal fentanyl tablets

To use sublingual tablets, follow the steps below:

• Remove one blister unit from the blister card.
• Pull back the foil to open the blister unit.... Do not remove the tablet from the foil or try to force it out of the foil.
• Do not open the blister until ready to use.
• Place the tablet in the mouth and between the cheek and gum, near the upper back teeth or under the tongue, as far as possible in the back of the mouth.
• Allow the tablet to dissolve completely....this process may take 14 to 25 minutes.
• Do not cut the tablet in half and do not chew it....also do not swallow it whole.
• If after 30 minutes there is still some tablet left in your mouth, swallow it with a sip of water.
• If you feel dizzy, drowsy or nauseous before the pill is completely dissolved, rinse your mouth with water and spit the rest of the pill into the sink or toilet.
• Wash the toilet or sink with water to remove the remnants of the pills.

Learn more: Diclofenac

Fentanyl dose calculation

The dose of this drug is adjusted based on factors such as age, body weight, physical condition, underlying diseases and concomitant medications. The desired dose for different groups is as follows:

1... Fentanyl dosage in anesthesia

The dose of this drug for anesthesia is:

• Intravenous (IV) bolus injection: The usual dose includes an initial dose of 1 to 2 micrograms per kilogram of body weight..
• Continuous infusion: After the initial injection, a continuous infusion (injecting a drug or liquid into the body continuously and at a controlled rate) can be adjusted to 5 micrograms per kilogram of body weight.. and sedation is necessary.

2... Fentanyl dose in infants

The dose of this medicine for babies is:

• Selective endotracheal intubation: intravenous dose of four micrograms per kilogram injected over three minutes.
Intravenous (IV) bolus injection: 1 to 2 mcg/kg over three minutes, repeated every 2 to 4 hours if needed.
• Continuous infusion: one to five micrograms per kilogram per hour adjusted according to the response and clinical condition of the baby.

3... Fentanyl dose in children

The dose of this medicine for children is:

• Intravenous (IV) bolus injection: one microgram per kilogram is injected over 2 minutes. The maximum dose allowed at one time is 50 micrograms. This dose may be repeated every 15 minutes if needed. But it requires careful monitoring to check for side effects.
• Intranasal version: When intravenous access is not possible, fentanyl can be used intranasally. The initial dose is 1.5 μg/kg, and in case of insufficient relief, a second dose of 0.75 to 1.5 μg/kg is prescribed 10 minutes later.

4... Fentanyl dose in adults

The dose of this medicine for adults is:

• Anesthesia: As an adjunct to general anesthesia, an initial dose of 50 to 100 micrograms intravenously can be prescribed, and if needed, additional doses of 25 to 50 micrograms are prescribed for pain relief.... For larger surgeries, higher doses may be required, adjusted according to patient needs.
• Management of acute pain: For severe acute pain, an initial dose of 25 to 50 mcg IV is prescribed, and subsequent doses are adjusted based on patient response.
Chronic pain management: Fentanyl skin patches are commonly used in patients with chronic pain.. These patches provide a continuous dose of fentanyl over 72 hours and are available in doses of 12 to 100 mcg/h.

Learn more: Alfen XL 100 tablets

Side effects of taking fentanyl tablets

The most common side effects of fentanyl are:

• Headache, dizziness and sleepiness
• pale, feeling weak or tired
• Constipation, nausea, vomiting and stomach pain
• Sleep problems such as insomnia
• hand or foot swelling
• Increased sweating or feeling cold
• itching, redness or skin rash at the glue site (if glue is used)

This drug may have other serious side effects....See a pain specialist right away if you experience any of the following symptoms:

• Severe allergic reactions such as hives, difficulty breathing, swelling of the face, lips, tongue, or throat
• Decreased heart rate, sighing, shallow breathing or sleep apnea
• Severe sleepiness or feeling faint
Confusion, extreme fear, unusual thoughts or behavior
• Decreased cortisol levels such as nausea, vomiting, loss of appetite, dizziness, weakness or severe fatigue
Symptoms of serotonin syndrome such as restlessness, hallucinations, fever, sweating, chills, fast heart rate, muscle stiffness or spasms, loss of coordination, nausea, vomiting, or diarrhea

Precautions before use or Contraindications

Before taking this medicine, pay attention to the following points:

• Fentanyl, like other narcotic drugs, slows breathing... In case of severe respiratory failure, death is possible.
• Using this medicine in the elderly may cause malnutrition or severe weakness.
• Long-term use of this drug may affect fertility (ability to bear children) in men and women... but it is not yet clear whether these effects are permanent.
• If you are using fentanyl patch and have a fever, tell your doctor.... High temperature can cause more absorption of the drug through the skin.
• Never change the type of medicine (sublingual tablet, skin patch, etc.) without consulting a doctor.. because the dosage is different in each form of medicine.
• Fentanyl use during pregnancy can cause dangerous withdrawal symptoms in the baby after birth. Therefore, avoid arbitrarily taking this medicine during pregnancy.
• Avoid taking this medicine during breastfeeding.

Learn more: Sumatriptan

Fentanyl drug interactions

Fentanyl interacts with many medications and may cause serious side effects or even death.. Tell your doctor if you are taking antibiotics, antifungal medications, heart or blood pressure medications, anti-seizure medications, or medications for HIV and hepatitis C... Drug interactions with fentanyl include:

• Other morphine-like drugs such as narcotic pain relievers or prescription cough syrups
Sedatives such as Diazepam, Alprazolam, Lorazepam, Ativan, Klonopin, Tranxen, Xanax and...
• Sedatives or drugs that slow breathing, such as sleeping pills, muscle relaxants, sedatives, antidepressants, and antipsychotics
• Medicines for colds, allergies, asthma and chronic obstructive pulmonary disease (COPD)
• Diuretic drugs
Medicines for motion sickness, irritable bowel syndrome and overactive bladder
• Medications that affect serotonin levels, including antidepressants, Parkinson's treatments, migraine medications, anticonvulsants, or antinausea and vomiting medications

Diseases related to fentanyl tablets

This drug is a strong and synthetic opiate substance, the incorrect use of which can cause serious problems for people's health. Its effects can be divided into short-term and long-term side effects.

1.... Health problems associated with fentanyl in the short term

The side effects of taking this medicine for the health of the body in the short term are:

• Respiration suppression
• Risk of overdose
Confusion and impaired consciousness
• Nausea and vomiting

2.... Long-term health problems associated with fentanyl

The long-term side effects of taking this medicine for body health are:

• Physical dependence and addiction
Chronic constipation
• breathing problems during sleep such as sleep apnea
• cardiovascular problems
Hormonal and reproductive disorders
• Mental disorders

People vulnerable to fentanyl drug

If you have any of the following conditions, you should not use this medicine:

• You are allergic to this medicine.
• You suffer from stomach or intestinal obstruction.
• You have severe asthma or severe breathing problems.

Also, to make sure this medicine is safe to use, tell your doctor if you have any of the following:

• Respiratory problems, sleep apnea
• head injury, brain tumor or mental illness
Alcohol or drug addiction Urinary problems
• Epilepsy or convulsions
• Liver or kidney disease
Gallbladder, pancreas or thyroid problems

Drug interactions in the body

By binding to certain receptors in the brain and spinal cord, especially mu-opioid receptors, fentanyl reduces the transmission of pain messages in the nervous system. This connection creates a chain reaction in which the production of a substance called cAMP decreases. The decrease in cAMP causes calcium ions to enter the cell, reducing the lead process and reducing the activity of cells.

Comparison of fentanyl and morphine

Both fentanyl and morphine are strong narcotic drugs used for pain control, but there are significant differences in potency, pharmacokinetics, uses, and risks.. The differences between these two drugs are:

• Fentanyl is approximately 100 times stronger than morphine.
• Fentanyl has a fast onset of action and its duration of action is shorter than that of morphine.
Morphine has a slower onset of action and a longer duration of action
• Morpine is commonly used to relieve moderate to severe pain and is available in various forms such as oral tablets and injectable solutions.
Fentanyl is mostly prescribed for severe or chronic pain... especially for patients who have become resistant to other opioids.
• Fentanyl is produced in forms such as skin patches, tablets that dissolve in the mouth, and injectable solutions.
• Both drugs can cause side effects such as respiratory depression and drowsiness. However, due to its high potency, fentanyl carries the risk of overdose and can be fatal.

Physician's Guide

In this article, we answered the question, what is fentanyl and what are its uses? In addition, we also examined the side effects, methods of use and dosage suitable for each person. As mentioned, fentanyl is a strong pain reliever that is used to relieve severe pain, especially in cancer patients.

Despite its high effectiveness, improper use of this drug can lead to dependence, abuse and even death from overdose... because fentanyl interacts with many drugs and its improper use can cause serious risks... so we recommend that you consult a pain specialist before taking this medicine... for this you can visit the website of GCORP.. LLC, including consult the best pain specialist.. Also GCORP LLC It gives you the possibility to make an appointment with the specialist of your choice through the internet appointment system.

Frequently Asked Questions