Overactive bladder is an annoying and unpleasant disease in which a person is unable to control the output of urine from his bladder and usually suffers from leakage of urine or unwanted discharge. This disease, which is often accompanied by symptoms such as urinary incontinence, urgency and frequency of urination, occurs due to muscle weakness related to the bladder or other muscle problems. In the bladder, it reduces involuntary contractions and helps to increase the capacity of the bladder..

If you also have symptoms of overactive bladder and your doctor has just prescribed this pill for you, join us in an upcoming article from GCORP LLC health magazine to review the properties and side effects of tolterodine.

What is tolterodine pill?

Tolterodine tablets (Tolterodine) under the brand name Detrol is an anticholinergic drug that is prescribed to treat overactive bladder. This drug affects the chemical that contracts the bladder muscles and reduces it to reduce involuntary spasm of the bladder muscles...

The slow-release capsule is another form of this drug, which is available in 2 and 4 mg doses... It is up to the urologist to determine whether a patient should take tolterodine tablets or capsules for overactive bladder.

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The mechanism of action of tolterodine tablets

The mechanism of action of this pill is based on the effect on certain receptors in the bladder that are effective in regulating its muscle contractions.... This drug is specifically an antagonist of muscarinic receptors (M3) and reduces the activity of parasympathetic nerves that are responsible for stimulating the bladder muscles... M3 stimulating receptors, the smooth muscle wall, are the main responsible for the contraction of the b receptors of the bladder... and empty urine... By blocking these receptors, tolterodine reduces the involuntary contractions of the bladder and increases its capacity.

What is Toltrodine 2 tablets for?

Different doses of this drug are prescribed by the doctor to treat overactive bladder with the following symptoms:

• Urinary incontinence
• Urine frequency
• Urgency in emptying urine
• Sudden need to urinate

How to take Toltrodine tablets

This medicine must be taken according to the doctor's prescription... The amount and dosage of the medicine is determined by the doctor based on the age, the patient's medical conditions, how the body responds to the treatment, the type and severity of the disease for each person.... Normally, tolterodine tablets are prescribed twice a day and slow-release capsules at a dose of four milligrams per day... The doctor usually starts the use of tolterodine tablets in children with the lowest dose and gradually increases it if needed.

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Important points when taking Toltrodine 2 tablets and its other doses include the following:

• The amount of medicine may be different from one person to another.. So don't increase the dose arbitrarily.
• Take the medicine completely after the treatment period.
• This tablet should be swallowed with a full glass of water.. So avoid crushing, breaking or chewing it.
• Tolterodine can be taken with or without food.
• If you have digestive problems, it is better to take this pill with food.
• The effectiveness of tolterodine lasts for several weeks.. Therefore, if the symptoms of the disease do not decrease after taking several doses, avoid stopping or changing the dose of the drug arbitrarily.
• If you forget to take a dose of medicine, take the missed dose as soon as you remember. But if the next dose of medicine is close (less than four hours), you can ignore the missed dose and continue taking the medicine as prescribed by the doctor.
• Remember, to make up for the missed dose, do not take 2 doses of the drug at the same time... because the possibility of drug side effects increases.
• If you experience severe gastrointestinal side effects after taking this medicine, be sure to inform your doctor so that he can replace tolterodine with another medicine if possible.

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The best time to take tolterodine

The appropriate time to take this medicine depends on the treatment goals and the doctor's recommendation... If the doctor has prescribed 2 doses of tolterodine for you, it is better to take the doses 12 hours apart (morning and night)... Also remember that it is very important to take the medicine at a certain time every day so that a constant dose remains in the body.

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Precautions and contraindications of tolterodine

This medicine should be used with caution in the presence of the following conditions and diseases, and it may be contraindicated in some cases.

• sensitivity to pill ingredients
• Family or personal history of heart problems
Liver and kidney problems hyperthyroidism Glaucoma eye disease
• High blood pressure
• Difficulty urinating such as bladder obstruction or urinary retention
Myasthenia gravis muscle disease
• Prostate problem
• Obstructive disorders of the digestive system and reduced movements of the digestive system
• Low blood potassium and magnesium
• Existence of symptoms such as sweating, vomiting and severe diarrhea

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Tolterodine tablets in pregnancy and breastfeeding

Currently, sufficient human research has not been done on the effect of this drug on the fetus during pregnancy.... Therefore, its use is not recommended without a doctor's prescription.... Therefore, if you are pregnant or planning to become pregnant, be sure to consult a gynecologist before taking different doses of tolterodine...

Also, the use of tolterodine tablets during breastfeeding is not approved.... Because so far, no study has been conducted on the transmission of the components of this drug through breast milk to the baby, and its side effects are not known... Therefore, it is better to avoid taking this drug arbitrarily during breastfeeding.

Possible side effects of tolterodine 2

Different doses of this pill may be associated with a series of side effects like any other drug, including the following:

Common side effects

These side effects are usually mild and resolve on their own after a few days:

• Headache
• dizziness
• fatigue
• Blurred vision
dry mouth
• Constipation
• Dry eyes
• stomach discomfort
• Sinusitis
• joint pain
sleepiness
• diarrhea

Serious side effects

The following symptoms are serious side effects of this pill, and if you see them, you should immediately stop taking the medicine and inform your doctor:

• severe abdominal and stomach pain
• Serious changes in vision
• Feeling pain when urinating
• Slow or irregular heartbeat
• chest pain
• Difficulty in breathing
• weight gain
• Symptoms of kidney infection such as back pain, painful urination, burning during urination and fever
• Allergic reaction such as itching, skin rash, swelling of the face, tongue, throat and lips

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Drug interactions of tolterodine

Drug interaction reduces the effectiveness of this pill and can increase the possibility of side effects. Drugs that may interact with tolterodine include:

• Anticholinergic drugs such as atropine and scopolamine
• Antispasmodic drugs such as dicyclomine and propantheline
• Some antiparkinsonian drugs such as benztropine and trihexyphenidyl
• Some antibiotics such as erythromycin
Antihistamines such as diphenhydramine and cetirizine
• hypnotics and sedatives such as alprazolam and diazepam
• muscle relaxants
Pain relievers such as codeine
• Potassium tablets and capsules

Guide to see a doctor

Tolterodine tablet is an effective drug in the treatment of symptoms caused by overactive bladder, such as urinary incontinence, urinary frequency, and urinary urgency.... By inhibiting muscarinic receptors in the bladder muscles, this drug reduces its involuntary activity and improves the quality of life. If you have more questions about the safety and effectiveness of tolterodine capsule for your specific conditions, you can refer to the website GCORP talk to the best LLC.. Doctors including nephrology doctor online consultation.... GCORP LLC also provides you with the possibility to make an appointment with the specialist of your choice through the online appointment system to personally Refer to nephrology doctor.

Frequently Asked Questions

Sources: webmd | medlineplus