What is the osteoporosis vaccine? There are a number of drug treatments for osteoporosis, some of which can be used in the form of ampoules. The most common ones are zoledronic acid, which is given to the patient once a year for 3 years, and denosumab, which is injected subcutaneously every 6 months. Denosumab is a human antibody that disables the biological mechanism that causes bone fracture, but does not prevent bone formation. ### Which ampoule is suitable for treating osteoporosis? Considering that one out of every three women over 50 years of age suffers from fractures related to osteoporosis, currently osteoporosis is one of the biggest health crises. But luckily, there are more options than ever to treat osteoporosis and restore normal bone strength. One of the newest treatments for osteoporosis that has entered the market is the osteoporosis ampoule. Unlike more traditional bone medications that come in pill or capsule form, injections for osteoporosis are usually given only a few times a year. It is important to pay attention to the way of taking medicines because not following the doctor's instructions in using their medicines is one of the primary health risks for men and women with osteoporosis. Researchers have found that only 40 percent of patients continue their treatments for more than a year, which is shocking. Osteoporosis injection options After the initial diagnosis of osteoporosis, most doctors first try a special type of medication called bisphosphonates. Then, depending on the reaction of the patient's body and also taking into account risk factors, the doctor may substitute another ampoule for osteoporosis. ### Bisphosphonates Most types of bisphosphonates are taken as daily, weekly, or monthly pills, but there is one brand name Reclast (zoledronic acid) that can be given as an intravenous injection. In cases where the goal is to prevent osteoporosis, for example, if there is a family history and the risk of developing this disease is high, the injection is done every two years. People with osteoporosis should be vaccinated once a year. ### Prolia (Denosumab) According to the National Osteoporosis Foundation, denosumab (brand name Prolia) has been one of the most effective treatments for osteoporosis. According to some reports, this drug reduces the risk of spinal fracture by about 70%. Denosumab works by deactivating the stimulator of osteoclasts, bone cells that weaken bones. It is given twice a year. One of the known drawbacks of denosumab is its effect on blood calcium levels. The National Osteoporosis Foundation warns: "Patients should have a blood test after each dose to ensure that blood calcium levels are not abnormally low." Symptoms of low calcium levels include muscle spasms, jumping or cramping, or numbness and tingling in the fingers, toes, or around the mouth. If any of these symptoms occur while taking this medication, patients should contact their healthcare provider. Read more: Osteoporosis due to aging + treatment ### Forteo (Triparatide) Triparatide, commonly known as Forteo, must be self-administered daily. This drug is supplied as a pre-filled injection pen, and each pen contains four weeks of medicine. It is a hormone treatment, albeit a synthetic, man-made hormone. For people with osteoporosis who cannot take steroid drugs, this drug is ideal. Forteo is the only ampoule on the market that specifically targets osteoblasts (good bone-forming cells) and directly improves bone density faster. Studies have shown that these daily injections are more effective in building bone density than bisphosphonates, but the injections can only be used for up to two years. After this period, its effect stops and the bones quickly lose their strength and density. Teriparatide injection is also associated with a rare but higher risk of some types of bone cancer. ### Furtical or Myacalcin (calcitonin) This drug, which is a synthetic hormone, is specifically designed for postmenopausal women. In fact, the ideal candidates for this drug are women who have been five years or more past menopause and have not had good results from other treatments. This hormone can help increase bone density, especially in the spine, as well as slow down the process of bone breakdown. Calcitonin is administered as a nasal spray or subcutaneous injection. However, calcitonin is one of the least effective osteoporosis drugs. But its reduced potency, which we mentioned above, means that it has less serious side effects compared to some of the above treatments. Pain or nosebleeds are the most common side effects. Read more: Osteoporosis physiotherapy in Shiraz Deciding on the choice of osteoporosis vaccine The doctor can provide the necessary explanations about each injection you choose for osteoporosis and explain their specific advantages and disadvantages for each person's health, as well as the risk factors and the appropriate dosage. In this way, you can be sure of the effectiveness of these treatments in protecting bone health and preventing falls, fractures, and other injuries. Bone density can be measured with a machine that uses low levels of X-rays to determine the ratio of minerals in the bones. During this painless test, the person lies on a padded table and a scanner passes over their body. In most cases, only certain bones are examined, usually the pelvis and spine. In severe cases of osteoporosis or when more common treatments for osteoporosis are not effective, your doctor may recommend trying the following: - Triparatide (Bencity, Forteo) - Abaloparatide (Thimlos) - Romosuzumab (Evenity) After diagnosis, osteoporosis needs treatment to protect bone health. Medicines are prescribed by a general practitioner or specialist. A wide range of treatment options are available. The patient and his doctor will determine the best treatment, taking into account the patient's other diseases and health problems. Calcium and vitamin D supplements may be recommended to the patient along with injectable treatment. For people with very severe osteoporosis or at risk of fracture, injectable treatments can be used instead of zoledronic acid or denosumab to build new bone faster. These bone-building drugs work by activating new bone-forming cells, while having a less and slower effect on the process of bone breakdown. Teriparatide and romosuzumab are other drugs available for the treatment of osteoporosis.